Matches in SemOpenAlex for { <https://semopenalex.org/work/W2990073923> ?p ?o ?g. }
- W2990073923 abstract "The aim of this study was to determine the antimicrobial efficiency of piperitenone epoxide (PEO) - a principal component of various aromatic plants' essential oil - in combination with various antibiotics against twenty eight strains of Staphylococcus aureus and ten strains of Escherichia coli isolated from clinical samples. Mentha spicata’s essential oil, initially collected by hydrodistillation, was then subjected to flush column chromatography affording PEO of high purity. Minimum Inhibitory Concentrations (MIC) of PEO alone and in combination with various concentrations of synthesized antibiotics was assessed by using the micro dilution method. The combined action was estimated calculating the Fractional Inhibitory Concentration Index (FICI) from checkerboard assays. Our results showed that the average MIC (mg/L) of PEO alone against E. coli was 512 ± 364.7 μg/mL which was significantly higher than 172.8 ± 180.7 μg/mL observed for S. aureus. From checkerboard assays, FIC values below the 0.5 index, indicating synergy, were observed for 59% of the synthesized drugs tested. Twelve percent of FIC index values were between 0.5 and 1 indicating additive effects, while 21% were indifferent. According to our results, PEO could be a promising antimicrobial compound when combined with specific antibiotics and deserves further study." @default.
- W2990073923 created "2019-12-05" @default.
- W2990073923 creator A5001330192 @default.
- W2990073923 creator A5001621043 @default.
- W2990073923 creator A5004134616 @default.
- W2990073923 creator A5008534106 @default.
- W2990073923 creator A5027134337 @default.
- W2990073923 creator A5030517060 @default.
- W2990073923 creator A5033554296 @default.
- W2990073923 creator A5035050571 @default.
- W2990073923 creator A5047281963 @default.
- W2990073923 creator A5065405468 @default.
- W2990073923 creator A5075094506 @default.
- W2990073923 creator A5081921160 @default.
- W2990073923 date "2019-11-19" @default.
- W2990073923 modified "2023-09-27" @default.
- W2990073923 title "Combined Action of Piperitenone Epoxide and Antibiotics Against Clinical Isolates of Staphylococcus aureus and Escherichia coli" @default.
- W2990073923 cites W1874122563 @default.
- W2990073923 cites W1964171417 @default.
- W2990073923 cites W1970057042 @default.
- W2990073923 cites W1972819159 @default.
- W2990073923 cites W1972989473 @default.
- W2990073923 cites W1973187109 @default.
- W2990073923 cites W1975300180 @default.
- W2990073923 cites W1976656293 @default.
- W2990073923 cites W1991386043 @default.
- W2990073923 cites W1992413291 @default.
- W2990073923 cites W1994669498 @default.
- W2990073923 cites W2000322530 @default.
- W2990073923 cites W2005493706 @default.
- W2990073923 cites W2005854408 @default.
- W2990073923 cites W2007601631 @default.
- W2990073923 cites W2009716530 @default.
- W2990073923 cites W2011419948 @default.
- W2990073923 cites W2016301590 @default.
- W2990073923 cites W2016562927 @default.
- W2990073923 cites W2016763331 @default.
- W2990073923 cites W2017881722 @default.
- W2990073923 cites W2018689960 @default.
- W2990073923 cites W2018710400 @default.
- W2990073923 cites W2025832072 @default.
- W2990073923 cites W2028388446 @default.
- W2990073923 cites W2031381859 @default.
- W2990073923 cites W2041504833 @default.
- W2990073923 cites W2042779053 @default.
- W2990073923 cites W2046062465 @default.
- W2990073923 cites W2048860386 @default.
- W2990073923 cites W2050028164 @default.
- W2990073923 cites W2052512407 @default.
- W2990073923 cites W2057679851 @default.
- W2990073923 cites W2061995450 @default.
- W2990073923 cites W2074641515 @default.
- W2990073923 cites W2076566905 @default.
- W2990073923 cites W2077464454 @default.
- W2990073923 cites W2078248663 @default.
- W2990073923 cites W2079751402 @default.
- W2990073923 cites W2093312055 @default.
- W2990073923 cites W2097164667 @default.
- W2990073923 cites W2103827483 @default.
- W2990073923 cites W2105644826 @default.
- W2990073923 cites W2107427748 @default.
- W2990073923 cites W2111004683 @default.
- W2990073923 cites W2112211112 @default.
- W2990073923 cites W2114472928 @default.
- W2990073923 cites W2117373577 @default.
- W2990073923 cites W2122910156 @default.
- W2990073923 cites W2133079687 @default.
- W2990073923 cites W2138063004 @default.
- W2990073923 cites W2139203278 @default.
- W2990073923 cites W2140656258 @default.
- W2990073923 cites W2154400082 @default.
- W2990073923 cites W2158921004 @default.
- W2990073923 cites W2164168857 @default.
- W2990073923 cites W2167896918 @default.
- W2990073923 cites W2176496726 @default.
- W2990073923 cites W2500796653 @default.
- W2990073923 cites W2534160503 @default.
- W2990073923 cites W2551233896 @default.
- W2990073923 cites W2784300996 @default.
- W2990073923 cites W2898382104 @default.
- W2990073923 cites W2899841051 @default.
- W2990073923 cites W4239569810 @default.
- W2990073923 doi "https://doi.org/10.3389/fmicb.2019.02607" @default.
- W2990073923 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6877480" @default.
- W2990073923 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31803154" @default.
- W2990073923 hasPublicationYear "2019" @default.
- W2990073923 type Work @default.
- W2990073923 sameAs 2990073923 @default.
- W2990073923 citedByCount "4" @default.
- W2990073923 countsByYear W29900739232021 @default.
- W2990073923 countsByYear W29900739232023 @default.
- W2990073923 crossrefType "journal-article" @default.
- W2990073923 hasAuthorship W2990073923A5001330192 @default.
- W2990073923 hasAuthorship W2990073923A5001621043 @default.
- W2990073923 hasAuthorship W2990073923A5004134616 @default.
- W2990073923 hasAuthorship W2990073923A5008534106 @default.
- W2990073923 hasAuthorship W2990073923A5027134337 @default.
- W2990073923 hasAuthorship W2990073923A5030517060 @default.
- W2990073923 hasAuthorship W2990073923A5033554296 @default.
- W2990073923 hasAuthorship W2990073923A5035050571 @default.