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- W2990498061 abstract "Objective: To investigate the efficacy and clinical value of transcatheter arterial chemoembolization (TACE) combined with ultrasound-guided microwave ablation for the treatment of liver cancer in special sites. Methods: The patients with liver cancer in special sites (the liver cancer was adjacent to the gallbladder, dome of diaphragm, gastrointestinal tract, heart, great vessels, and portal vein, with the shortest distance from the tumor to the organ/lumen < 0.5 cm ) were enrolled as treatment group, and the patients with primary liver cancer in normal sites treated in our hospital during the same period were randomly enrolled as control group. They underwent TACE combined with ultrasound-guided microwave ablation. The 6-month, 12-month, 18-month and 24-month survival rates of the patients in two groups were analyzed. Results: The clinical data of 40 patients with liver cancer in special sites, including 9, 7, 5, 11, 3, 3, and 2 patients with liver cancer adjacent to the gallbladder, dome of diaphragm, gastrointestinal tract, portal vein, hepatic vein, inferior vena cava, and heart, respectively, and another 40 patients in control group were collected in the study. The negative rate of alpha-fetoprotein (AFP) was 83.3% in the treatment group and 82.8% in the control group. The 6-month, 12-month, 18-month, and 24-month survival rates were 100.0%, 95.0%, 90.0%, and 80.0%, respectively, in the treatment group, and 100.0%, 97.5%, 92.5%, and 85.0%, respectively, in the control group. Conclusion: TACE combined with ultrasound-guided microwave ablation is as effective for liver cancer in special sites as for those in normal sites, with high safety, and is feasible in clinical application.目的： 探讨肝动脉化学治疗栓塞联合超声引导下微波消融术治疗特殊部位肝癌的疗效及应用价值。 方法： 选取徐州医科大学附属医院特殊部位（临近胆囊、膈顶、胃肠、心脏、大血管、肝门管道的肝癌，且肿瘤距上述脏器或管腔的最短距离< 0.5 cm）肝癌患者作为治疗组，并通过分层随机选取同期普通部位原发性肝癌患者作为对照组，采取肝动脉化学治疗栓塞后联合超声引导下微波消融治疗，随访统计6个月、12个月、18个月、24个月生存率。计量资料的比较采用t检验，计数资料的比较采用卡方检验，生存曲线分析采用Kaplan-Meier分析，Log-rank检验。 结果： 共收集40例特殊部位肝癌（邻近胆囊9例、膈顶7例、胃肠5例、门静脉11例、肝静脉3例、下腔静脉3例、心脏2例）患者资料,40例对照组资料。治疗组及对照组甲胎蛋白转阴率为83.3%和82.8%；治疗组6个月、12个月、18个月、24个月生存率分别为100.0%、95.0%、90.0%、80.0%，对照组6个月、12个月、18个月、24个月生存率分别为100.0%、97.5%、92.5%、85.0%。 结论： 肝动脉化学治疗栓塞术联合超声引导下微波消融术对治疗特殊部位肝癌确切有效，其疗效与普通部位肝癌疗效相近，安全性高，可于临床广泛应用。." @default.
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- W2990498061 date "2017-12-20" @default.
- W2990498061 modified "2023-09-23" @default.
- W2990498061 title "[Therapeutic effect of transcatheter arterial chemoembolization combined with ultrasound-guided microwave ablation for treatment of liver cancer in special sites]." @default.
- W2990498061 doi "https://doi.org/10.3760/cma.j.issn.1007-3418.2017.12.006" @default.
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