Matches in SemOpenAlex for { <https://semopenalex.org/work/W2990499407> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2990499407 endingPage "107602961989042" @default.
- W2990499407 startingPage "107602961989042" @default.
- W2990499407 abstract "Vitamin K antagonists, such as warfarin, have a narrow therapeutic window; patients on these therapies therefore require regular international normalized ratio (INR) monitoring to maintain optimal dosing. This involves periodic checks and laboratory testing using venepuncture, which are often perceived as a burden. This study aimed to determine the accuracy and precision of the LumiraDx INR Test, a new point-of-care in vitro diagnostic platform, in an anticoagulation clinic setting. In this observational, cross-sectional study, precision of the LumiraDx INR Test was assessed using paired replicate samples (n = 366) and 3 test strip lots. Accuracy was determined by comparing capillary blood INR, ascertained by the LumiraDx INR Test, with venous plasma INR, measured by the laboratory reference instrument, the IL ACL ELITE Pro. Furthermore, INR was assessed across a range of hematocrit (25%-55%). In addition, feedback was collected from health-care professionals via a self-completed questionnaire. This trial was registered at ClinicalTrials.gov (NCT03682419). The precision (% coefficient of variation) of the LumiraDx INR Test was <4 when samples were applied by direct application or via a capillary transfer pipette, as well as between test strip lots. Accuracy of the LumiraDx INR Test, across the INR range of 0.8 to 7.5, was confirmed by a strong correlation of 0.965 (95% confidence interval: 0.959-0.970) when compared with the IL ACL ELITE Pro, which was maintained across the hematocrit range. Feedback from health-care professionals indicated that the instructions given by the system were easy to follow. In conclusion, the strong agreement between the LumiraDx Platform INR point-of-care test and the IL ACL ELITE Pro laboratory reference system, as well as between the different application methods and test lots, indicates that it can provide a rapid, accurate, and reliable INR analysis." @default.
- W2990499407 created "2019-12-05" @default.
- W2990499407 creator A5001125056 @default.
- W2990499407 creator A5038999177 @default.
- W2990499407 creator A5080476873 @default.
- W2990499407 date "2019-01-01" @default.
- W2990499407 modified "2023-10-13" @default.
- W2990499407 title "Performance of the LumiraDx Platform INR Test in an Anticoagulation Clinic Point-of-Care Setting Compared With an Established Laboratory Reference Method" @default.
- W2990499407 cites W1548076363 @default.
- W2990499407 cites W1976770571 @default.
- W2990499407 cites W2137455218 @default.
- W2990499407 cites W2142521193 @default.
- W2990499407 cites W2174003732 @default.
- W2990499407 cites W2323559086 @default.
- W2990499407 cites W2422502774 @default.
- W2990499407 cites W2532336617 @default.
- W2990499407 cites W2772427721 @default.
- W2990499407 cites W2811381416 @default.
- W2990499407 cites W2890761654 @default.
- W2990499407 cites W2902233584 @default.
- W2990499407 cites W2968873359 @default.
- W2990499407 cites W4211129082 @default.
- W2990499407 doi "https://doi.org/10.1177/1076029619890423" @default.
- W2990499407 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7019395" @default.
- W2990499407 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31773973" @default.
- W2990499407 hasPublicationYear "2019" @default.
- W2990499407 type Work @default.
- W2990499407 sameAs 2990499407 @default.
- W2990499407 citedByCount "2" @default.
- W2990499407 countsByYear W29904994072022 @default.
- W2990499407 countsByYear W29904994072023 @default.
- W2990499407 crossrefType "journal-article" @default.
- W2990499407 hasAuthorship W2990499407A5001125056 @default.
- W2990499407 hasAuthorship W2990499407A5038999177 @default.
- W2990499407 hasAuthorship W2990499407A5080476873 @default.
- W2990499407 hasBestOaLocation W29904994071 @default.
- W2990499407 hasConcept C105795698 @default.
- W2990499407 hasConcept C126322002 @default.
- W2990499407 hasConcept C141071460 @default.
- W2990499407 hasConcept C142724271 @default.
- W2990499407 hasConcept C151730666 @default.
- W2990499407 hasConcept C1862650 @default.
- W2990499407 hasConcept C2776301958 @default.
- W2990499407 hasConcept C2777267654 @default.
- W2990499407 hasConcept C2777357209 @default.
- W2990499407 hasConcept C2779161974 @default.
- W2990499407 hasConcept C2780959883 @default.
- W2990499407 hasConcept C33923547 @default.
- W2990499407 hasConcept C44249647 @default.
- W2990499407 hasConcept C51915194 @default.
- W2990499407 hasConcept C64841741 @default.
- W2990499407 hasConcept C71924100 @default.
- W2990499407 hasConcept C74414138 @default.
- W2990499407 hasConcept C86803240 @default.
- W2990499407 hasConcept C89838059 @default.
- W2990499407 hasConceptScore W2990499407C105795698 @default.
- W2990499407 hasConceptScore W2990499407C126322002 @default.
- W2990499407 hasConceptScore W2990499407C141071460 @default.
- W2990499407 hasConceptScore W2990499407C142724271 @default.
- W2990499407 hasConceptScore W2990499407C151730666 @default.
- W2990499407 hasConceptScore W2990499407C1862650 @default.
- W2990499407 hasConceptScore W2990499407C2776301958 @default.
- W2990499407 hasConceptScore W2990499407C2777267654 @default.
- W2990499407 hasConceptScore W2990499407C2777357209 @default.
- W2990499407 hasConceptScore W2990499407C2779161974 @default.
- W2990499407 hasConceptScore W2990499407C2780959883 @default.
- W2990499407 hasConceptScore W2990499407C33923547 @default.
- W2990499407 hasConceptScore W2990499407C44249647 @default.
- W2990499407 hasConceptScore W2990499407C51915194 @default.
- W2990499407 hasConceptScore W2990499407C64841741 @default.
- W2990499407 hasConceptScore W2990499407C71924100 @default.
- W2990499407 hasConceptScore W2990499407C74414138 @default.
- W2990499407 hasConceptScore W2990499407C86803240 @default.
- W2990499407 hasConceptScore W2990499407C89838059 @default.
- W2990499407 hasLocation W29904994071 @default.
- W2990499407 hasLocation W29904994072 @default.
- W2990499407 hasLocation W29904994073 @default.
- W2990499407 hasLocation W29904994074 @default.
- W2990499407 hasLocation W29904994075 @default.
- W2990499407 hasLocation W29904994076 @default.
- W2990499407 hasOpenAccess W2990499407 @default.
- W2990499407 hasPrimaryLocation W29904994071 @default.
- W2990499407 hasRelatedWork W1644347037 @default.
- W2990499407 hasRelatedWork W2331462147 @default.
- W2990499407 hasRelatedWork W2579213687 @default.
- W2990499407 hasRelatedWork W2806818597 @default.
- W2990499407 hasRelatedWork W2888278163 @default.
- W2990499407 hasRelatedWork W2926342017 @default.
- W2990499407 hasRelatedWork W2990499407 @default.
- W2990499407 hasRelatedWork W3134795082 @default.
- W2990499407 hasRelatedWork W41721774 @default.
- W2990499407 hasRelatedWork W4230837717 @default.
- W2990499407 hasVolume "25" @default.
- W2990499407 isParatext "false" @default.
- W2990499407 isRetracted "false" @default.
- W2990499407 magId "2990499407" @default.
- W2990499407 workType "article" @default.