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- W2990553738 abstract "Education may play a key role in developing “cognitive reserve” against neurodegenerative dementia. In this work, we investigate for the first time if handwriting dynamics can serve as a quantitative indicator of this reserve. We carried out an exploratory study involving a sample of mild cognitive impairment (MCI) subjects, with high and low education respectively, and a sample of healthy elder controls. We asked them to perform three complex handwriting tasks on a digitizing tablet: drawing a clock; copying a check; writing a spontaneous sentence. Dynamic measures of the handwriting were then analyzed both with an unsupervised and a supervised machine learning approach. The results we obtained suggest that: (i) handwriting of MCI subjects with high reserve is quite similar to that of controls; (ii) handwriting of MCI subjects with lower reserve is easier to be distinguished from the other two. Dynamic handwriting analysis could provide a novel methodology to elucidate the still unknown mechanisms underlying brain resilience." @default.
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- W2990553738 date "2019-10-01" @default.
- W2990553738 modified "2023-10-16" @default.
- W2990553738 title "Handwriting Dynamics as an Indicator of Cognitive Reserve: An Exploratory Study" @default.
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- W2990553738 doi "https://doi.org/10.1109/smc.2019.8914157" @default.
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