FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2990596107> ?p ?o ?g. }

• W2990596107 abstract "Abstract Astellatol is a synthetically highly challenging sesterterpenoid that possesses a congested pentacyclic ring system, which contains 10 stereocenters, a unique bicyclo[4.1.1]octane motif, a cyclobutane moiety that possesses two quaternary centers, an exo-methylene group, and a sterically encumbered isopropyl trans-hydrindane motif. Herein, we describe the full account of our synthesis of astellatol, including two generations of synthetic design and corresponding experimental attempts. The key transformations of our synthetic strategy include a facile construction of 5/7-bicyclic motif, an intramolecular Pauson–Khand reaction that quickly constructed the hydrindane scaffold, a SmI2-induced reductive radical 1,6-addition that successfully forged the cyclobutane ring, and a key strategic late-stage reduction of a fully substituted olefin that produced the critical trans-hydrindane moiety of astellatol." @default.
• W2990596107 created "2019-12-05" @default.
• W2990596107 creator A5011497989 @default.
• W2990596107 creator A5057123149 @default.
• W2990596107 date "2019-01-01" @default.
• W2990596107 modified "2023-09-24" @default.
• W2990596107 title "Enantiospecific total synthesis of the sesterterpenoid astellatol" @default.
• W2990596107 cites W1991214228 @default.
• W2990596107 cites W1992259722 @default.
• W2990596107 cites W1996055906 @default.
• W2990596107 cites W2000515566 @default.
• W2990596107 cites W2001223890 @default.
• W2990596107 cites W2002104633 @default.
• W2990596107 cites W2012659227 @default.
• W2990596107 cites W2015734041 @default.
• W2990596107 cites W2015752493 @default.
• W2990596107 cites W2017228080 @default.
• W2990596107 cites W2022784472 @default.
• W2990596107 cites W2024258562 @default.
• W2990596107 cites W2055874107 @default.
• W2990596107 cites W2060573862 @default.
• W2990596107 cites W2062756316 @default.
• W2990596107 cites W2097995096 @default.
• W2990596107 cites W2125921790 @default.
• W2990596107 cites W2128651232 @default.
• W2990596107 cites W2140490499 @default.
• W2990596107 cites W2152735339 @default.
• W2990596107 cites W2154109654 @default.
• W2990596107 cites W2155106053 @default.
• W2990596107 cites W2155198007 @default.
• W2990596107 cites W2161695514 @default.
• W2990596107 cites W2166868299 @default.
• W2990596107 cites W2239949517 @default.
• W2990596107 cites W2292470149 @default.
• W2990596107 cites W2318593126 @default.
• W2990596107 cites W2333913569 @default.
• W2990596107 cites W2344126488 @default.
• W2990596107 cites W2379482688 @default.
• W2990596107 cites W2418323390 @default.
• W2990596107 cites W2460039299 @default.
• W2990596107 cites W2513308195 @default.
• W2990596107 cites W2560879722 @default.
• W2990596107 cites W2566768125 @default.
• W2990596107 cites W2605202858 @default.
• W2990596107 cites W2791654828 @default.
• W2990596107 cites W2805482251 @default.
• W2990596107 cites W2890699248 @default.
• W2990596107 cites W2898942056 @default.
• W2990596107 cites W2950625915 @default.
• W2990596107 cites W2952203058 @default.
• W2990596107 doi "https://doi.org/10.1016/b978-0-12-814805-1.00005-3" @default.
• W2990596107 hasPublicationYear "2019" @default.
• W2990596107 type Work @default.
• W2990596107 sameAs 2990596107 @default.
• W2990596107 citedByCount "1" @default.
• W2990596107 countsByYear W29905961072023 @default.
• W2990596107 crossrefType "book-chapter" @default.
• W2990596107 hasAuthorship W2990596107A5011497989 @default.
• W2990596107 hasAuthorship W2990596107A5057123149 @default.
• W2990596107 hasConcept C104264131 @default.
• W2990596107 hasConcept C134195300 @default.
• W2990596107 hasConcept C146686406 @default.
• W2990596107 hasConcept C155647269 @default.
• W2990596107 hasConcept C161790260 @default.
• W2990596107 hasConcept C178790620 @default.
• W2990596107 hasConcept C185592680 @default.
• W2990596107 hasConcept C201194858 @default.
• W2990596107 hasConcept C21951064 @default.
• W2990596107 hasConcept C24961977 @default.
• W2990596107 hasConcept C2776568683 @default.
• W2990596107 hasConcept C2777454769 @default.
• W2990596107 hasConcept C2780159532 @default.
• W2990596107 hasConcept C2780377690 @default.
• W2990596107 hasConcept C2780378348 @default.
• W2990596107 hasConcept C35753019 @default.
• W2990596107 hasConcept C71240020 @default.
• W2990596107 hasConcept C75079739 @default.
• W2990596107 hasConceptScore W2990596107C104264131 @default.
• W2990596107 hasConceptScore W2990596107C134195300 @default.
• W2990596107 hasConceptScore W2990596107C146686406 @default.
• W2990596107 hasConceptScore W2990596107C155647269 @default.
• W2990596107 hasConceptScore W2990596107C161790260 @default.
• W2990596107 hasConceptScore W2990596107C178790620 @default.
• W2990596107 hasConceptScore W2990596107C185592680 @default.
• W2990596107 hasConceptScore W2990596107C201194858 @default.
• W2990596107 hasConceptScore W2990596107C21951064 @default.
• W2990596107 hasConceptScore W2990596107C24961977 @default.
• W2990596107 hasConceptScore W2990596107C2776568683 @default.
• W2990596107 hasConceptScore W2990596107C2777454769 @default.
• W2990596107 hasConceptScore W2990596107C2780159532 @default.
• W2990596107 hasConceptScore W2990596107C2780377690 @default.
• W2990596107 hasConceptScore W2990596107C2780378348 @default.
• W2990596107 hasConceptScore W2990596107C35753019 @default.
• W2990596107 hasConceptScore W2990596107C71240020 @default.
• W2990596107 hasConceptScore W2990596107C75079739 @default.
• W2990596107 hasLocation W29905961071 @default.
• W2990596107 hasOpenAccess W2990596107 @default.
• W2990596107 hasPrimaryLocation W29905961071 @default.
• W2990596107 hasRelatedWork W1990738528 @default.
• W2990596107 hasRelatedWork W2017402110 @default.

• next