Matches in SemOpenAlex for { <https://semopenalex.org/work/W2990608800> ?p ?o ?g. }
- W2990608800 abstract "The discovery of the role of kisspeptin neurons in the regulation of mammalian reproduction in 2003 was one of the biggest breakthroughs in reproductive endocrinology within the last few decades. Research during the past two decades since the discovery of kisspeptin has been unveiling the mechanism of how the hypothalamic kisspeptin neurons control reproductive functions through regulation of gonadotropin-releasing hormone (GnRH) secretion. This article aims to overview kisspeptin research, including the most recent studies from ours and other research groups, and to discuss the possibility of new strategies to control reproductive functions in farm animals. In the first section, we introduce the critical role of kisspeptin neurons in puberty onset and reproductive functions in mammals, including the regulation of two modes of GnRH/gonadotropin secretion, namely pulsatile and surge modes. The next section focuses more on the mechanism of how the kisspeptin neurons in the arcuate nucleus in the hypothalamus precisely controls GnRH pulse using other two neuropeptides, neurokinin B and dynorphin A. The article also discusses the mechanism suppressing reproductive function during lactation and other stress conditions through inhibition of kisspeptin neurons and consequent GnRH/gonadotropin secretion, to provide insights on the possibility of new strategies to control reproductive performance in domestic farm animals. Keywords Anteroventral Periventricular Nucleus, Arcuate Nucleus, Fertility, Gonadotropins, Pre-optic Area." @default.
- W2990608800 created "2019-12-05" @default.
- W2990608800 creator A5011916922 @default.
- W2990608800 creator A5016204078 @default.
- W2990608800 creator A5078622682 @default.
- W2990608800 creator A5080622561 @default.
- W2990608800 creator A5088383123 @default.
- W2990608800 date "2019-11-11" @default.
- W2990608800 modified "2023-09-23" @default.
- W2990608800 title "Kisspeptin: A Central Regulator of Reproduction in Mammals" @default.
- W2990608800 cites W1644061906 @default.
- W2990608800 cites W1732962922 @default.
- W2990608800 cites W1880891411 @default.
- W2990608800 cites W1963600515 @default.
- W2990608800 cites W1963923625 @default.
- W2990608800 cites W1966035579 @default.
- W2990608800 cites W1972038183 @default.
- W2990608800 cites W1975400348 @default.
- W2990608800 cites W1975890243 @default.
- W2990608800 cites W1984028801 @default.
- W2990608800 cites W1984879501 @default.
- W2990608800 cites W1984902037 @default.
- W2990608800 cites W1990370237 @default.
- W2990608800 cites W1993199844 @default.
- W2990608800 cites W1993413620 @default.
- W2990608800 cites W1996713062 @default.
- W2990608800 cites W1997375921 @default.
- W2990608800 cites W2005121205 @default.
- W2990608800 cites W2010920434 @default.
- W2990608800 cites W2021344960 @default.
- W2990608800 cites W2028307321 @default.
- W2990608800 cites W2028777780 @default.
- W2990608800 cites W2030585597 @default.
- W2990608800 cites W2032969797 @default.
- W2990608800 cites W2037848559 @default.
- W2990608800 cites W2045555035 @default.
- W2990608800 cites W2045690475 @default.
- W2990608800 cites W2046824138 @default.
- W2990608800 cites W2052236652 @default.
- W2990608800 cites W2057268569 @default.
- W2990608800 cites W2057451219 @default.
- W2990608800 cites W2058782486 @default.
- W2990608800 cites W2066627511 @default.
- W2990608800 cites W2081895094 @default.
- W2990608800 cites W2083906980 @default.
- W2990608800 cites W2084810464 @default.
- W2990608800 cites W2100081913 @default.
- W2990608800 cites W2101853789 @default.
- W2990608800 cites W2106332614 @default.
- W2990608800 cites W2107197791 @default.
- W2990608800 cites W2111338104 @default.
- W2990608800 cites W2121303720 @default.
- W2990608800 cites W2121771034 @default.
- W2990608800 cites W2127864011 @default.
- W2990608800 cites W2141217442 @default.
- W2990608800 cites W2143506157 @default.
- W2990608800 cites W2167619569 @default.
- W2990608800 cites W2169968838 @default.
- W2990608800 cites W2405746451 @default.
- W2990608800 cites W2475281166 @default.
- W2990608800 cites W2610576732 @default.
- W2990608800 cites W2728987308 @default.
- W2990608800 cites W2904819411 @default.
- W2990608800 cites W2908987283 @default.
- W2990608800 doi "https://doi.org/10.21608/svu.2019.16569.1027" @default.
- W2990608800 hasPublicationYear "2019" @default.
- W2990608800 type Work @default.
- W2990608800 sameAs 2990608800 @default.
- W2990608800 citedByCount "1" @default.
- W2990608800 countsByYear W29906088002022 @default.
- W2990608800 crossrefType "journal-article" @default.
- W2990608800 hasAuthorship W2990608800A5011916922 @default.
- W2990608800 hasAuthorship W2990608800A5016204078 @default.
- W2990608800 hasAuthorship W2990608800A5078622682 @default.
- W2990608800 hasAuthorship W2990608800A5080622561 @default.
- W2990608800 hasAuthorship W2990608800A5088383123 @default.
- W2990608800 hasBestOaLocation W29906088001 @default.
- W2990608800 hasConcept C118303440 @default.
- W2990608800 hasConcept C126322002 @default.
- W2990608800 hasConcept C134018914 @default.
- W2990608800 hasConcept C170493617 @default.
- W2990608800 hasConcept C2776533618 @default.
- W2990608800 hasConcept C2776808119 @default.
- W2990608800 hasConcept C2777003273 @default.
- W2990608800 hasConcept C2778458369 @default.
- W2990608800 hasConcept C2778575703 @default.
- W2990608800 hasConcept C2778894405 @default.
- W2990608800 hasConcept C2781359426 @default.
- W2990608800 hasConcept C71315377 @default.
- W2990608800 hasConcept C71924100 @default.
- W2990608800 hasConcept C86803240 @default.
- W2990608800 hasConceptScore W2990608800C118303440 @default.
- W2990608800 hasConceptScore W2990608800C126322002 @default.
- W2990608800 hasConceptScore W2990608800C134018914 @default.
- W2990608800 hasConceptScore W2990608800C170493617 @default.
- W2990608800 hasConceptScore W2990608800C2776533618 @default.
- W2990608800 hasConceptScore W2990608800C2776808119 @default.
- W2990608800 hasConceptScore W2990608800C2777003273 @default.
- W2990608800 hasConceptScore W2990608800C2778458369 @default.
- W2990608800 hasConceptScore W2990608800C2778575703 @default.