Matches in SemOpenAlex for { <https://semopenalex.org/work/W2990720099> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2990720099 endingPage "1070" @default.
- W2990720099 startingPage "1065" @default.
- W2990720099 abstract "Objective: To study the gross morphology of skeletal muscles and plasma Creatinine phosphokinase levels of rats and find effect of long acting β2-agonists co-administration in Statin induced myopathies.Study Design: Quasi experimental study.Place and Duration of Study: Department of Anatomy, Army Medical College Rawalpindi in collaboration with National Institute of Health (NIH) Islamabad and Armed forces institute of Pathology (AFIP) Rawalpindi, from Jan 2015 to Jun 2016.Methodology: Adult male Sprague-Dawley rats were procured from NIH Islamabad. Their average approximate age was 70-80 days with weight range 250 ± 50 grams. The animals were randomly selected and divided into three groups. Group A was the control. Each rat of group B received Simvastatin dissolved in distilled water, by oral gavage (60mg/kg/day) once daily, for 12 weeks. Animals of Group C received simvastatin dissolved in distilled water, (60mg/kg/day) once daily plus for dissolved in distilled water (3μg/kg/day) once daily for 12 weeks. 5ml sample of blood was taken in a plain tube directly from the heart for the quantitative measurement of creatine phosphokinase (CPK) levels before sacrificing of the animals. The animals were sacrificed after three months of the experimental period.Results: Examination of plasma levels of CPK of the control group revealed the normal values. It was significantly higher in group B as compared to the control group A. The serum creatine phosphokinase levels showed a decrease in the mean levels after treatment with Formoterol in group CConclusion: Simvastatin induced the myopathic changes in the skeletal muscle of experimental rats which was shown by increased CPK levels. Formoterol co-administration decreased CPK levels in simvastatin induced myopathies." @default.
- W2990720099 created "2019-12-05" @default.
- W2990720099 creator A5020276916 @default.
- W2990720099 creator A5042525865 @default.
- W2990720099 creator A5063610740 @default.
- W2990720099 creator A5089048897 @default.
- W2990720099 date "2019-10-23" @default.
- W2990720099 modified "2023-09-23" @default.
- W2990720099 title "Effect of long acting beta 2-agonist on gross morphology of skeletal muscles and creatine phosphokinase level in simvastatin induced myopathies in rats" @default.
- W2990720099 hasPublicationYear "2019" @default.
- W2990720099 type Work @default.
- W2990720099 sameAs 2990720099 @default.
- W2990720099 citedByCount "0" @default.
- W2990720099 crossrefType "journal-article" @default.
- W2990720099 hasAuthorship W2990720099A5020276916 @default.
- W2990720099 hasAuthorship W2990720099A5042525865 @default.
- W2990720099 hasAuthorship W2990720099A5063610740 @default.
- W2990720099 hasAuthorship W2990720099A5089048897 @default.
- W2990720099 hasConcept C126322002 @default.
- W2990720099 hasConcept C126894567 @default.
- W2990720099 hasConcept C134018914 @default.
- W2990720099 hasConcept C140793950 @default.
- W2990720099 hasConcept C2776329913 @default.
- W2990720099 hasConcept C2779896295 @default.
- W2990720099 hasConcept C2780306776 @default.
- W2990720099 hasConcept C36880943 @default.
- W2990720099 hasConcept C71924100 @default.
- W2990720099 hasConcept C86803240 @default.
- W2990720099 hasConceptScore W2990720099C126322002 @default.
- W2990720099 hasConceptScore W2990720099C126894567 @default.
- W2990720099 hasConceptScore W2990720099C134018914 @default.
- W2990720099 hasConceptScore W2990720099C140793950 @default.
- W2990720099 hasConceptScore W2990720099C2776329913 @default.
- W2990720099 hasConceptScore W2990720099C2779896295 @default.
- W2990720099 hasConceptScore W2990720099C2780306776 @default.
- W2990720099 hasConceptScore W2990720099C36880943 @default.
- W2990720099 hasConceptScore W2990720099C71924100 @default.
- W2990720099 hasConceptScore W2990720099C86803240 @default.
- W2990720099 hasIssue "5" @default.
- W2990720099 hasOpenAccess W2990720099 @default.
- W2990720099 hasRelatedWork W2070035323 @default.
- W2990720099 hasRelatedWork W2141182169 @default.
- W2990720099 hasRelatedWork W2360054560 @default.
- W2990720099 hasRelatedWork W2385090936 @default.
- W2990720099 hasRelatedWork W2417543594 @default.
- W2990720099 hasRelatedWork W2748226031 @default.
- W2990720099 hasRelatedWork W2916054501 @default.
- W2990720099 hasRelatedWork W2984178471 @default.
- W2990720099 hasRelatedWork W2992444940 @default.
- W2990720099 hasRelatedWork W3014866692 @default.
- W2990720099 hasRelatedWork W3030797851 @default.
- W2990720099 hasRelatedWork W3031022204 @default.
- W2990720099 hasRelatedWork W3031709428 @default.
- W2990720099 hasRelatedWork W3042320532 @default.
- W2990720099 hasRelatedWork W3134071466 @default.
- W2990720099 hasRelatedWork W3138664011 @default.
- W2990720099 hasRelatedWork W3151301850 @default.
- W2990720099 hasRelatedWork W2182398336 @default.
- W2990720099 hasRelatedWork W2187472702 @default.
- W2990720099 hasRelatedWork W2187818762 @default.
- W2990720099 hasVolume "69" @default.
- W2990720099 isParatext "false" @default.
- W2990720099 isRetracted "false" @default.
- W2990720099 magId "2990720099" @default.
- W2990720099 workType "article" @default.