Matches in SemOpenAlex for { <https://semopenalex.org/work/W2990795623> ?p ?o ?g. }
- W2990795623 endingPage "46650" @default.
- W2990795623 startingPage "46645" @default.
- W2990795623 abstract "Diagnosis of prostate cancer via PCA3 biomarker detection is promising to be much more efficient than with the prostatic specific antigens currently used. In this study, we present the first electrochemical and impedance-based biosensors that are capable of detecting PCA3 down to 0.128 nmol/L. The biosensors were made with a layer of PCA3-complementary single-stranded DNA (ssDNA) probe, immobilized on a layer-by-layer (LbL) film of chitosan (CHT) and carbon nanotubes (MWCNT). They are highly selective to PCA3, which was confirmed in impedance measurements and with polarization-modulated infrared reflection absorption spectroscopy (PM-IRRAS). Using information visualization methods, we could also distinguish between cell lines expressing the endogenous PCA3 long noncoding RNA (lncRNA) from cells that did not contain detectable levels of this biomarker. Since the methods involved in fabrication the biosensors are potentially low cost, one may hope to deploy PCA3 tests in any laboratory of clinical analyses and even for point-of-care diagnostics." @default.
- W2990795623 created "2019-12-05" @default.
- W2990795623 creator A5013859983 @default.
- W2990795623 creator A5015399447 @default.
- W2990795623 creator A5031124934 @default.
- W2990795623 creator A5035432368 @default.
- W2990795623 creator A5036264012 @default.
- W2990795623 creator A5063400456 @default.
- W2990795623 creator A5072941726 @default.
- W2990795623 creator A5085794154 @default.
- W2990795623 date "2019-11-25" @default.
- W2990795623 modified "2023-10-17" @default.
- W2990795623 title "Detection of the Prostate Cancer Biomarker PCA3 with Electrochemical and Impedance-Based Biosensors" @default.
- W2990795623 cites W1801362421 @default.
- W2990795623 cites W1975146750 @default.
- W2990795623 cites W1993002585 @default.
- W2990795623 cites W1996820400 @default.
- W2990795623 cites W2005092210 @default.
- W2990795623 cites W2009040055 @default.
- W2990795623 cites W2019549684 @default.
- W2990795623 cites W2023834245 @default.
- W2990795623 cites W2023936383 @default.
- W2990795623 cites W2028826331 @default.
- W2990795623 cites W2034802727 @default.
- W2990795623 cites W2037594142 @default.
- W2990795623 cites W2044780723 @default.
- W2990795623 cites W2064298508 @default.
- W2990795623 cites W2069239591 @default.
- W2990795623 cites W2072317160 @default.
- W2990795623 cites W2082359809 @default.
- W2990795623 cites W2084341845 @default.
- W2990795623 cites W2100001326 @default.
- W2990795623 cites W2139934719 @default.
- W2990795623 cites W2160947271 @default.
- W2990795623 cites W2168138611 @default.
- W2990795623 cites W2169385858 @default.
- W2990795623 cites W2205510568 @default.
- W2990795623 cites W2233973795 @default.
- W2990795623 cites W2261191213 @default.
- W2990795623 cites W2274832362 @default.
- W2990795623 cites W2294124296 @default.
- W2990795623 cites W2564315848 @default.
- W2990795623 cites W2736006547 @default.
- W2990795623 cites W2742828015 @default.
- W2990795623 cites W2746384296 @default.
- W2990795623 cites W2765871708 @default.
- W2990795623 cites W2794276221 @default.
- W2990795623 cites W2896021293 @default.
- W2990795623 cites W2911188335 @default.
- W2990795623 cites W2963254963 @default.
- W2990795623 doi "https://doi.org/10.1021/acsami.9b19180" @default.
- W2990795623 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31765118" @default.
- W2990795623 hasPublicationYear "2019" @default.
- W2990795623 type Work @default.
- W2990795623 sameAs 2990795623 @default.
- W2990795623 citedByCount "55" @default.
- W2990795623 countsByYear W29907956232020 @default.
- W2990795623 countsByYear W29907956232021 @default.
- W2990795623 countsByYear W29907956232022 @default.
- W2990795623 countsByYear W29907956232023 @default.
- W2990795623 crossrefType "journal-article" @default.
- W2990795623 hasAuthorship W2990795623A5013859983 @default.
- W2990795623 hasAuthorship W2990795623A5015399447 @default.
- W2990795623 hasAuthorship W2990795623A5031124934 @default.
- W2990795623 hasAuthorship W2990795623A5035432368 @default.
- W2990795623 hasAuthorship W2990795623A5036264012 @default.
- W2990795623 hasAuthorship W2990795623A5063400456 @default.
- W2990795623 hasAuthorship W2990795623A5072941726 @default.
- W2990795623 hasAuthorship W2990795623A5085794154 @default.
- W2990795623 hasBestOaLocation W29907956232 @default.
- W2990795623 hasConcept C121608353 @default.
- W2990795623 hasConcept C126322002 @default.
- W2990795623 hasConcept C160756335 @default.
- W2990795623 hasConcept C171250308 @default.
- W2990795623 hasConcept C185592680 @default.
- W2990795623 hasConcept C192562407 @default.
- W2990795623 hasConcept C2780192828 @default.
- W2990795623 hasConcept C2781197716 @default.
- W2990795623 hasConcept C55493867 @default.
- W2990795623 hasConcept C71924100 @default.
- W2990795623 hasConcept C87874733 @default.
- W2990795623 hasConceptScore W2990795623C121608353 @default.
- W2990795623 hasConceptScore W2990795623C126322002 @default.
- W2990795623 hasConceptScore W2990795623C160756335 @default.
- W2990795623 hasConceptScore W2990795623C171250308 @default.
- W2990795623 hasConceptScore W2990795623C185592680 @default.
- W2990795623 hasConceptScore W2990795623C192562407 @default.
- W2990795623 hasConceptScore W2990795623C2780192828 @default.
- W2990795623 hasConceptScore W2990795623C2781197716 @default.
- W2990795623 hasConceptScore W2990795623C55493867 @default.
- W2990795623 hasConceptScore W2990795623C71924100 @default.
- W2990795623 hasConceptScore W2990795623C87874733 @default.
- W2990795623 hasFunder F4320320997 @default.
- W2990795623 hasFunder F4320322025 @default.
- W2990795623 hasIssue "50" @default.
- W2990795623 hasLocation W29907956231 @default.
- W2990795623 hasLocation W29907956232 @default.
- W2990795623 hasLocation W29907956233 @default.