Matches in SemOpenAlex for { <https://semopenalex.org/work/W2990805534> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2990805534 endingPage "260" @default.
- W2990805534 startingPage "253" @default.
- W2990805534 abstract "Abstract In this work we formulate a hybrid multiscale model for describing the fundamental immune processes in human immunodeficiency type 1 (HIV) infection. These include (i) the T cell migration in the lymphoid tissue, (ii) the replication cycle of HIV within an infected cell, (iii) the type I interferon (IFN) response of the target cells, and (iv) the spatiotemporal dynamics of the HIV and type I IFN fields. Computational implementation of the hybrid multiscale model is presented. It is based on the use of semi-implicit first-order symplectic Euler method for solving the equations of the second Newton’s law for cell migration and the alternating direction method for the initial-boundary value problem for reaction–diffusion equations governing the spatial evolution of the virus and IFN fields in 2D domain representing the lymph node (LN) tissue. Both, the stochastic and deterministic descriptions of the intracellular HIV infection and the IFN reaction are developed. The potential of the calibrated multiscale hybrid model is illustrated by predicting the dynamics of the local HIV infection bursts in LN tissue." @default.
- W2990805534 created "2019-12-05" @default.
- W2990805534 creator A5061601583 @default.
- W2990805534 creator A5073874945 @default.
- W2990805534 date "2019-10-25" @default.
- W2990805534 modified "2023-09-25" @default.
- W2990805534 title "Spatially resolved modelling of immune responses following a multiscale approach: from computational implementation to quantitative predictions" @default.
- W2990805534 cites W1963963990 @default.
- W2990805534 cites W2003081219 @default.
- W2990805534 cites W2062629162 @default.
- W2990805534 cites W2065006175 @default.
- W2990805534 cites W2089692155 @default.
- W2990805534 cites W2091174660 @default.
- W2990805534 cites W2109513727 @default.
- W2990805534 cites W2122723212 @default.
- W2990805534 cites W2127301185 @default.
- W2990805534 cites W2162742070 @default.
- W2990805534 cites W2177381833 @default.
- W2990805534 cites W2568445566 @default.
- W2990805534 cites W2618154116 @default.
- W2990805534 cites W2677052639 @default.
- W2990805534 cites W2761672801 @default.
- W2990805534 cites W2808147913 @default.
- W2990805534 cites W2913461384 @default.
- W2990805534 cites W2941165494 @default.
- W2990805534 cites W2947191936 @default.
- W2990805534 cites W2951729257 @default.
- W2990805534 doi "https://doi.org/10.1515/rnam-2019-0021" @default.
- W2990805534 hasPublicationYear "2019" @default.
- W2990805534 type Work @default.
- W2990805534 sameAs 2990805534 @default.
- W2990805534 citedByCount "3" @default.
- W2990805534 countsByYear W29908055342020 @default.
- W2990805534 countsByYear W29908055342023 @default.
- W2990805534 crossrefType "journal-article" @default.
- W2990805534 hasAuthorship W2990805534A5061601583 @default.
- W2990805534 hasAuthorship W2990805534A5073874945 @default.
- W2990805534 hasConcept C121332964 @default.
- W2990805534 hasConcept C121864883 @default.
- W2990805534 hasConcept C134306372 @default.
- W2990805534 hasConcept C159047783 @default.
- W2990805534 hasConcept C182310444 @default.
- W2990805534 hasConcept C28826006 @default.
- W2990805534 hasConcept C3013748606 @default.
- W2990805534 hasConcept C33923547 @default.
- W2990805534 hasConcept C36503486 @default.
- W2990805534 hasConcept C41008148 @default.
- W2990805534 hasConcept C86803240 @default.
- W2990805534 hasConceptScore W2990805534C121332964 @default.
- W2990805534 hasConceptScore W2990805534C121864883 @default.
- W2990805534 hasConceptScore W2990805534C134306372 @default.
- W2990805534 hasConceptScore W2990805534C159047783 @default.
- W2990805534 hasConceptScore W2990805534C182310444 @default.
- W2990805534 hasConceptScore W2990805534C28826006 @default.
- W2990805534 hasConceptScore W2990805534C3013748606 @default.
- W2990805534 hasConceptScore W2990805534C33923547 @default.
- W2990805534 hasConceptScore W2990805534C36503486 @default.
- W2990805534 hasConceptScore W2990805534C41008148 @default.
- W2990805534 hasConceptScore W2990805534C86803240 @default.
- W2990805534 hasIssue "5" @default.
- W2990805534 hasLocation W29908055341 @default.
- W2990805534 hasOpenAccess W2990805534 @default.
- W2990805534 hasPrimaryLocation W29908055341 @default.
- W2990805534 hasRelatedWork W1597420886 @default.
- W2990805534 hasRelatedWork W2028690217 @default.
- W2990805534 hasRelatedWork W2057170938 @default.
- W2990805534 hasRelatedWork W2057996673 @default.
- W2990805534 hasRelatedWork W2073968511 @default.
- W2990805534 hasRelatedWork W2623347760 @default.
- W2990805534 hasRelatedWork W2883819976 @default.
- W2990805534 hasRelatedWork W2912679009 @default.
- W2990805534 hasRelatedWork W3034138874 @default.
- W2990805534 hasRelatedWork W4377003472 @default.
- W2990805534 hasVolume "34" @default.
- W2990805534 isParatext "false" @default.
- W2990805534 isRetracted "false" @default.
- W2990805534 magId "2990805534" @default.
- W2990805534 workType "article" @default.