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- W2990907082 abstract "Drugs with anticholinergic action are widely prescribed in the elderly population due to their potential clinical benefits. However, these benefits are limited by adverse effects which may be serious in particular circumstances. This review presents different aspects of the use of anticholinergics in old age with a focus in psychogeriatric patients. We critically review published data on benefits and disadvantages of anticholinergics, which are often controversial. Prevalence, pathophysiology and measurement methods of the anticholinergic action of drugs are discussed. We also present the most important drawbacks resulting from its use, including effects on cognition in healthy and cognitively impaired people, in aged schizophrenia patients, emergence of delirium and psychiatric symptoms, influence in functionality, hospitalization, institutionalization and mortality, and the potential benefits and limitations of their discontinuation. Finally, we suggest practical recommendations for the safe use of anticholinergics in clinical conditions affecting elderly patients, such as dementia, schizophrenia and acute hallucinatory episodes, depression, anxiety, Parkinson's disease, cardiovascular conditions and urinary incontinence." @default.
- W2990907082 created "2019-12-05" @default.
- W2990907082 creator A5003669272 @default.
- W2990907082 creator A5022917042 @default.
- W2990907082 creator A5034019657 @default.
- W2990907082 date "2019-12-06" @default.
- W2990907082 modified "2023-10-18" @default.
- W2990907082 title "Anticholinergic Drugs in Geriatric Psychopharmacology" @default.
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