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- W2991036756 abstract "Microelectrode arrays are widely used in different fields such as neurobiology or biomedicine to read out electrical signals from cells or biomolecules. One way to improve microelectrode applications is the development of novel electrode materials with enhanced or additional functionality. In this study, we fabricated macroelectrodes and microelectrode arrays containing gold penetrated by nanohole arrays as a conductive layer. We used this holey gold to optically excite surface plasmon polaritons, which lead to a strong increase in transparency, an effect that is further enhanced by the plasmon's interaction with cell culture medium. By varying the nanohole diameter in finite-difference time domain simulations, we demonstrate that the transmission can be increased to above 70% with its peak at a wavelength depending on the holey gold's lattice constant. Further, we demonstrate that the novel transparent microelectrode arrays are as suitable for recording cellular electrical activity as standard devices. Moreover, we prove using spectral measurements and finite-difference time domain simulations that plasmonically induced transmission peaks of holey gold red-shift upon sensing medium or cells in close vicinity (<30 nm) to the substrate. Thus, we establish plasmonic and transparent holey gold as a tunable material suitable for cellular electrical recordings and biosensing applications." @default.
- W2991036756 created "2019-12-05" @default.
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- W2991036756 date "2019-11-22" @default.
- W2991036756 modified "2023-10-01" @default.
- W2991036756 title "MEA Recordings and Cell–Substrate Investigations with Plasmonic and Transparent, Tunable Holey Gold" @default.
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- W2991036756 doi "https://doi.org/10.1021/acsami.9b14948" @default.
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