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• W2991083721 abstract "Abstract Glycomics refers to the comprehensive analysis of glycans. Recent progress in glycotechnology enables the determination of a variety of biological functions of glycans. Among different glycosylation patterns, certain types of aberrant glycosylation are linked to cancer and/or inflammation, and thus have biological importance. Glycotechnology has been applied to many fields of medical science, including hepatology. In particular, dramatic changes in glycosylation are observed in the progression of liver diseases. As the liver produces so many serum glycoproteins, changes in glycosylation of these proteins might provide useful disease biomarkers. Furthermore, many patients with genetic diseases of glycosylation who have liver dysfunction have been found as a result from whole genome sequencing, and various kinds of glycotherapy have been developed, especially in immunotherapy. In this review, we describe our basic knowledge of glycobiology and discuss the application of these data to medical science, especially hepatology." @default.
• W2991083721 created "2019-12-05" @default.
• W2991083721 creator A5054250942 @default.
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• W2991083721 creator A5080369708 @default.
• W2991083721 date "2019-12-13" @default.
• W2991083721 modified "2023-10-14" @default.
• W2991083721 title "Functional glycomics: Application to medical science and hepatology" @default.
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• W2991083721 doi "https://doi.org/10.1111/hepr.13459" @default.
• W2991083721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31750967" @default.
• W2991083721 hasPublicationYear "2019" @default.
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