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- W2991109138 abstract "Prenatal exposure to mercury (T-Hg) comes from both natural and anthropogenic sources. T-Hg can cross the blood-placental barrier, transfer from mother to fetus, and may be associated with future neurological (memory loss, personality changes, deafness and vision loss, attenuation of IQ) and physiological (delays in walking and talking, tremors and convulsions) dysfunctions. Hair is an optimal and non-invasive indicator of chronic T-Hg exposure. On average, scalp hair grows about 1.1 cm per month. As part of the Maternal-Infant Research on Environmental Chemicals (MIREC) Study, hair samples of 350 women were collected within weeks after giving birth, to determine temporal variation of T-Hg from conception to delivery, and to compare these levels to levels measured in other matrices (maternal and umbilical cord blood, breast milk, and infant’s meconium). One centimeter sequential hair samples were collected, starting at the scalp and up to 12 cm. Overall, T-Hg levels decreased over the course of pregnancy. Mercury levels in hair positively correlated with levels in blood, but not with levels in meconium or breast milk. A higher mean mercury level was found in cord blood, meaning that it was able to pass the placental barrier, but did not reach the fetus, since the majority of meconium samples had mercury below the detection limit. This study generates knowledge on the monthly variation of mercury in a pan-Canadian pregnancy cohort and provides a unique opportunity to compare mercury levels from multiple matrices from pregnant women and their infants." @default.
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- W2991109138 date "2018-09-24" @default.
- W2991109138 modified "2023-09-23" @default.
- W2991109138 title "Temporal Variation of Total Mercury Levels in the Hair of Pregnant Women from the MIREC (Maternal-Infant Research on Environmental Chemicals) Study" @default.
- W2991109138 doi "https://doi.org/10.1289/isesisee.2018.p03.3230" @default.
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