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- W2991302912 abstract "Testing of an expanded, 800-compound set of analogues of the earlier described Strecker-type α-aminonitriles (selected from publicly available Enamine Ltd. Screening Collection) in thermal shift assay against bovine carbonic anhydrase (bCA) led to further validation of this new class of inhibitors and identification a new, refined chemotype represented by inhibitors with 10-improved potency." @default.
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- W2991302912 date "2019-11-22" @default.
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- W2991302912 title "Further validation of strecker-type α-aminonitriles as a new class of potent human carbonic anhydrase II inhibitors: hit expansion within the public domain using differential scanning fluorimetry leads to chemotype refinement" @default.
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- W2991302912 doi "https://doi.org/10.1080/14756366.2019.1693556" @default.
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