FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2991421568> ?p ?o ?g. }

• W2991421568 endingPage "e7828" @default.
• W2991421568 startingPage "e7828" @default.
• W2991421568 abstract "To investigate the correlation between the single nucleotide polymorphisms (SNPs) in the toll-like receptor 4 (TLR4) gene and the susceptibility to chronic periodontitis.241 Chinese subjects from the cohort of Beijing Shijingshan Community were recruited. Buccal swab samples, the whole unstimulated saliva and periodontal clinical parameters were collected. Human DNA extracted from buccal swab samples were used for genotyping eight SNPs of the TLR4 gene (rs11536889, rs1927906, rs1927911, rs2149356, rs4986790, rs4986791, rs2737190, rs787384) by the Sequenom MassARRAY system. Porphyromonas gingivalis (P. gingivalis) was detected from the deposition of the whole unstimulated saliva through polymerase chain reaction (PCR) method based on 16S rRNA. The correlation between SNPs of TLR4 and chronic periodontitis susceptibility in the whole subjects and the patients detected with P. gingivalis was investigated.The variants of rs4986790 and rs4986791 were not found in 241 Chinese subjects. Moreover, there was no significant difference in the distribution of theother6 SNPs of TLR4 between groups of none/mild -periodontitis and moderate/severe-periodontitis subjects. When combined with P. gingivalis infection, rs1927911 (TT/CC+CT), rs2149356 (TT/GG+GT) and rs2737190 (GG/AA+AG) were independent risk factors of chronic periodontitis.Three SNPs of TLR4, i.e., rs1927911 (TT/CC+CT), rs2149356 (TT/GG+GT) and rs2737190 (GG/AA+AG), were associated with moderate/severe chronic periodontitis in Chinese population infected with P. gingivalis. P. gingivalis, which interacted with TLR4 gene plays an important role in the pathogenesis of periodontitis." @default.
• W2991421568 created "2019-12-05" @default.
• W2991421568 creator A5004671640 @default.
• W2991421568 creator A5017088193 @default.
• W2991421568 creator A5053068973 @default.
• W2991421568 creator A5059734360 @default.
• W2991421568 creator A5071931173 @default.
• W2991421568 creator A5091566266 @default.
• W2991421568 date "2019-11-21" @default.
• W2991421568 modified "2023-09-29" @default.
• W2991421568 title "TLR4 polymorphisms may increase susceptibility to periodontitis in Pg-positive individuals" @default.
• W2991421568 cites W170467223 @default.
• W2991421568 cites W1800567007 @default.
• W2991421568 cites W1883473434 @default.
• W2991421568 cites W1960007290 @default.
• W2991421568 cites W1974560725 @default.
• W2991421568 cites W1975414790 @default.
• W2991421568 cites W1977990206 @default.
• W2991421568 cites W1987270912 @default.
• W2991421568 cites W1991340733 @default.
• W2991421568 cites W1998799665 @default.
• W2991421568 cites W2012306016 @default.
• W2991421568 cites W2016319683 @default.
• W2991421568 cites W2038935869 @default.
• W2991421568 cites W2040050761 @default.
• W2991421568 cites W2043204880 @default.
• W2991421568 cites W2061486008 @default.
• W2991421568 cites W2077933101 @default.
• W2991421568 cites W2092334833 @default.
• W2991421568 cites W2100524797 @default.
• W2991421568 cites W2107816137 @default.
• W2991421568 cites W2110356699 @default.
• W2991421568 cites W2117561115 @default.
• W2991421568 cites W2119764574 @default.
• W2991421568 cites W2129319296 @default.
• W2991421568 cites W2131684681 @default.
• W2991421568 cites W2132413368 @default.
• W2991421568 cites W2133664523 @default.
• W2991421568 cites W2136336700 @default.
• W2991421568 cites W2137147994 @default.
• W2991421568 cites W2147618198 @default.
• W2991421568 cites W2152096613 @default.
• W2991421568 cites W2156121631 @default.
• W2991421568 cites W2162935965 @default.
• W2991421568 cites W2224340016 @default.
• W2991421568 cites W2261850810 @default.
• W2991421568 cites W2358693996 @default.
• W2991421568 cites W2395322836 @default.
• W2991421568 cites W2409231317 @default.
• W2991421568 cites W2469045126 @default.
• W2991421568 cites W2490394056 @default.
• W2991421568 cites W157885687 @default.
• W2991421568 doi "https://doi.org/10.7717/peerj.7828" @default.
• W2991421568 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6875378" @default.
• W2991421568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31772831" @default.
• W2991421568 hasPublicationYear "2019" @default.
• W2991421568 type Work @default.
• W2991421568 sameAs 2991421568 @default.
• W2991421568 citedByCount "5" @default.
• W2991421568 countsByYear W29914215682020 @default.
• W2991421568 countsByYear W29914215682021 @default.
• W2991421568 countsByYear W29914215682022 @default.
• W2991421568 countsByYear W29914215682023 @default.
• W2991421568 crossrefType "journal-article" @default.
• W2991421568 hasAuthorship W2991421568A5004671640 @default.
• W2991421568 hasAuthorship W2991421568A5017088193 @default.
• W2991421568 hasAuthorship W2991421568A5053068973 @default.
• W2991421568 hasAuthorship W2991421568A5059734360 @default.
• W2991421568 hasAuthorship W2991421568A5071931173 @default.
• W2991421568 hasAuthorship W2991421568A5091566266 @default.
• W2991421568 hasBestOaLocation W29914215681 @default.
• W2991421568 hasConcept C104317684 @default.
• W2991421568 hasConcept C126322002 @default.
• W2991421568 hasConcept C135763542 @default.
• W2991421568 hasConcept C153209595 @default.
• W2991421568 hasConcept C153911025 @default.
• W2991421568 hasConcept C167871757 @default.
• W2991421568 hasConcept C203014093 @default.
• W2991421568 hasConcept C2779337755 @default.
• W2991421568 hasConcept C2780183776 @default.
• W2991421568 hasConcept C2780385504 @default.
• W2991421568 hasConcept C2908647359 @default.
• W2991421568 hasConcept C31467283 @default.
• W2991421568 hasConcept C504460877 @default.
• W2991421568 hasConcept C54355233 @default.
• W2991421568 hasConcept C71924100 @default.
• W2991421568 hasConcept C86803240 @default.
• W2991421568 hasConcept C99454951 @default.
• W2991421568 hasConceptScore W2991421568C104317684 @default.
• W2991421568 hasConceptScore W2991421568C126322002 @default.
• W2991421568 hasConceptScore W2991421568C135763542 @default.
• W2991421568 hasConceptScore W2991421568C153209595 @default.
• W2991421568 hasConceptScore W2991421568C153911025 @default.
• W2991421568 hasConceptScore W2991421568C167871757 @default.
• W2991421568 hasConceptScore W2991421568C203014093 @default.
• W2991421568 hasConceptScore W2991421568C2779337755 @default.
• W2991421568 hasConceptScore W2991421568C2780183776 @default.
• W2991421568 hasConceptScore W2991421568C2780385504 @default.

• next