FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2991435503> ?p ?o ?g. }

• W2991435503 abstract "Abstract Longitudinal in vivo micro-computed tomography (micro-CT) is of interest to non-invasively capture the healing process of individual animals in preclinical fracture healing studies. However, it is not known whether longitudinal imaging itself has an impact on callus formation and remodeling. In this study, a scan group received weekly micro-CT measurements (week 0–6), whereas controls were only scanned post-operatively and at week 5 and 6. Registration of consecutive scans using a branching scheme (bridged vs. unbridged defect) combined with a two-threshold approach enabled assessment of localized bone turnover and mineralization kinetics relevant for monitoring callus remodeling. Weekly micro-CT application did not significantly change any of the assessed callus parameters in the defect and periosteal volumes. This was supported by histomorphometry showing only small amounts of cartilage residuals in both groups, indicating progression towards the end of the healing period. Also, immunohistochemical staining of Sclerostin, previously associated with mediating adverse radiation effects on bone, did not reveal differences between groups. The established longitudinal in vivo micro-CT-based approach allows monitoring of healing phases in mouse femur defect models without significant effects of anesthesia, handling and radiation on callus properties. Therefore, this study supports application of longitudinal in vivo micro-CT for healing-phase-specific monitoring of fracture repair in mice." @default.
• W2991435503 created "2019-12-05" @default.
• W2991435503 creator A5005077691 @default.
• W2991435503 creator A5037956106 @default.
• W2991435503 creator A5059680717 @default.
• W2991435503 creator A5070750262 @default.
• W2991435503 creator A5089683524 @default.
• W2991435503 creator A5091827843 @default.
• W2991435503 date "2019-11-25" @default.
• W2991435503 modified "2023-10-01" @default.
• W2991435503 title "Evaluation of longitudinal time-lapsed in vivo micro-CT for monitoring fracture healing in mouse femur defect models" @default.
• W2991435503 cites W154770181 @default.
• W2991435503 cites W1970014815 @default.
• W2991435503 cites W1976824675 @default.
• W2991435503 cites W1978299166 @default.
• W2991435503 cites W1983119666 @default.
• W2991435503 cites W1988063973 @default.
• W2991435503 cites W1991821243 @default.
• W2991435503 cites W2000566575 @default.
• W2991435503 cites W2001756725 @default.
• W2991435503 cites W2006497932 @default.
• W2991435503 cites W2014567351 @default.
• W2991435503 cites W2021242322 @default.
• W2991435503 cites W2036728117 @default.
• W2991435503 cites W2039602359 @default.
• W2991435503 cites W2059863632 @default.
• W2991435503 cites W2060298455 @default.
• W2991435503 cites W2072100512 @default.
• W2991435503 cites W2077797036 @default.
• W2991435503 cites W2083449063 @default.
• W2991435503 cites W2087797033 @default.
• W2991435503 cites W2098095516 @default.
• W2991435503 cites W2098608227 @default.
• W2991435503 cites W2100185747 @default.
• W2991435503 cites W2103684286 @default.
• W2991435503 cites W2106138685 @default.
• W2991435503 cites W2111812542 @default.
• W2991435503 cites W2114852271 @default.
• W2991435503 cites W2123784063 @default.
• W2991435503 cites W2126416997 @default.
• W2991435503 cites W2126609373 @default.
• W2991435503 cites W2131026912 @default.
• W2991435503 cites W2131222823 @default.
• W2991435503 cites W2132098240 @default.
• W2991435503 cites W2134621908 @default.
• W2991435503 cites W2136906270 @default.
• W2991435503 cites W2152926978 @default.
• W2991435503 cites W2162442068 @default.
• W2991435503 cites W2163770969 @default.
• W2991435503 cites W2167279371 @default.
• W2991435503 cites W2168947658 @default.
• W2991435503 cites W2318583208 @default.
• W2991435503 cites W2408846913 @default.
• W2991435503 cites W2520228721 @default.
• W2991435503 cites W2560194693 @default.
• W2991435503 cites W2618654495 @default.
• W2991435503 cites W2619518937 @default.
• W2991435503 cites W2625702801 @default.
• W2991435503 cites W2755886301 @default.
• W2991435503 cites W2799683212 @default.
• W2991435503 cites W2802781008 @default.
• W2991435503 cites W2884083710 @default.
• W2991435503 cites W2886908391 @default.
• W2991435503 cites W2901281491 @default.
• W2991435503 cites W2946550968 @default.
• W2991435503 cites W2954841743 @default.
• W2991435503 cites W2965770091 @default.
• W2991435503 cites W4233381705 @default.
• W2991435503 cites W85456087 @default.
• W2991435503 doi "https://doi.org/10.1038/s41598-019-53822-x" @default.
• W2991435503 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6877534" @default.
• W2991435503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31768003" @default.
• W2991435503 hasPublicationYear "2019" @default.
• W2991435503 type Work @default.
• W2991435503 sameAs 2991435503 @default.
• W2991435503 citedByCount "35" @default.
• W2991435503 countsByYear W29914355032019 @default.
• W2991435503 countsByYear W29914355032020 @default.
• W2991435503 countsByYear W29914355032021 @default.
• W2991435503 countsByYear W29914355032022 @default.
• W2991435503 countsByYear W29914355032023 @default.
• W2991435503 crossrefType "journal-article" @default.
• W2991435503 hasAuthorship W2991435503A5005077691 @default.
• W2991435503 hasAuthorship W2991435503A5037956106 @default.
• W2991435503 hasAuthorship W2991435503A5059680717 @default.
• W2991435503 hasAuthorship W2991435503A5070750262 @default.
• W2991435503 hasAuthorship W2991435503A5089683524 @default.
• W2991435503 hasAuthorship W2991435503A5091827843 @default.
• W2991435503 hasBestOaLocation W29914355031 @default.
• W2991435503 hasConcept C105702510 @default.
• W2991435503 hasConcept C126322002 @default.
• W2991435503 hasConcept C126838900 @default.
• W2991435503 hasConcept C136229726 @default.
• W2991435503 hasConcept C141071460 @default.
• W2991435503 hasConcept C142724271 @default.
• W2991435503 hasConcept C150903083 @default.
• W2991435503 hasConcept C170033053 @default.
• W2991435503 hasConcept C207001950 @default.
• W2991435503 hasConcept C2777825092 @default.
• W2991435503 hasConcept C2780012534 @default.

• next