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• W2991521349 endingPage "108944" @default.
• W2991521349 startingPage "108944" @default.
• W2991521349 abstract "Bisphenols F (BPF) and S (BPS) are bisphenol A (BPA) analogs used as substitutes in consumer products. Despite previous reports of BPA's association with asthma, no studies have examined its structural analogs in relation to asthma and allergy outcomes. To examine the association of urinary BPF, BPS, and BPA with asthma and hay fever in a US representative sample. We analyzed data from 3,538 participants aged 12 years or older in the 2013–2016 National Health and Nutrition Examination Survey (NHANES). Children aged 6–11 years (N = 738), who did not have all covariate data available, were analyzed separately. Covariate-adjusted logistic regression was used to assess the association of the exposures with the outcomes. BPF, BPS, and BPA were detected in 57.1%, 88.4%, and 94.8% of the urine samples, respectively. Urinary BPF detection was positively associated with current asthma (odds ratio [OR]: 1.54, 95% confidence interval [CI]: 1.16–2.04) and hay fever (OR: 1.66, 95% CI: 1.12–2.46). Urinary BPS was associated with increased odds of current asthma in men (OR: 1.64, 95% CI: 1.13–2.40) and urinary BPA was associated with increased odds of asthma without hay fever in children aged 6–11 years (OR: 2.65, 95% CI: 1.05–6.68). Our nationally-representative findings document that BPF and BPS exposure is common in the US and that exposure to these BPA analogs is associated with asthma and/or hay fever. Our results suggest that BPF and BPS may not be safe alternatives to BPA; however, prospective studies should be conducted to confirm these results." @default.
• W2991521349 created "2019-12-05" @default.
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• W2991521349 date "2020-04-01" @default.
• W2991521349 modified "2023-10-18" @default.
• W2991521349 title "Association of urinary levels of bisphenols F and S used as bisphenol A substitutes with asthma and hay fever outcomes" @default.
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• W2991521349 doi "https://doi.org/10.1016/j.envres.2019.108944" @default.
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