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- W2991541566 endingPage "172829" @default.
- W2991541566 startingPage "172829" @default.
- W2991541566 abstract "Abstract Addiction to drug and alcohol is regarded as a major health problem worldwide for which available treatments show limited effectiveness. The biggest challenge remains to enhance the capacities of interventions to reduce craving, prevent relapse and promote long-term recovery. New strategies to meet these challenges are being explored. Findings from preclinical work suggest that environmental enrichment (EE) holds therapeutic potential for the treatment of substance use disorders, as demonstrated in a number of animal models of drug abuse. The EE intervention introduced after drug exposure leads to attenuation of compulsive drug taking, attenuation of the rewarding (and reinforcing) effects of drugs, reductions in control of behavior by drug cues, and, very importantly, relapse prevention. Clinical work also suggests that multidimensional EE interventions (involving physical activity, social interaction, vocational training, recreational and community involvement) might produce similar therapeutic effects, if implemented continuously and rigorously. In this review we survey preclinical and clinical studies assessing the efficacy of EE as a behavioral intervention for substance use disorders and address related challenges. We also review work providing empirical evidence for EE-induced neuroplasticity within the mesocorticolimbic system that is believed to contribute to the seemingly therapeutic effects of EE on drug and alcohol-related behaviors." @default.
- W2991541566 created "2019-12-05" @default.
- W2991541566 creator A5006209264 @default.
- W2991541566 creator A5035565515 @default.
- W2991541566 creator A5078983728 @default.
- W2991541566 date "2020-01-01" @default.
- W2991541566 modified "2023-09-29" @default.
- W2991541566 title "Therapeutic efficacy of environmental enrichment for substance use disorders" @default.
- W2991541566 cites W1000043755 @default.
- W2991541566 cites W1186181902 @default.
- W2991541566 cites W1198334849 @default.
- W2991541566 cites W1426165999 @default.
- W2991541566 cites W1449417130 @default.
- W2991541566 cites W1480115940 @default.
- W2991541566 cites W1482973198 @default.
- W2991541566 cites W1590727693 @default.
- W2991541566 cites W1595394563 @default.
- W2991541566 cites W1770934634 @default.
- W2991541566 cites W1789985606 @default.
- W2991541566 cites W1819517490 @default.
- W2991541566 cites W1862285350 @default.
- W2991541566 cites W1890045606 @default.
- W2991541566 cites W1913760354 @default.
- W2991541566 cites W1916096396 @default.
- W2991541566 cites W1936655670 @default.
- W2991541566 cites W1959902108 @default.
- W2991541566 cites W1965723380 @default.
- W2991541566 cites W1967292256 @default.
- W2991541566 cites W1968490092 @default.
- W2991541566 cites W1970516662 @default.
- W2991541566 cites W1970664844 @default.
- W2991541566 cites W1970728248 @default.
- W2991541566 cites W1971063627 @default.
- W2991541566 cites W1971366396 @default.
- W2991541566 cites W1971658792 @default.
- W2991541566 cites W1971769956 @default.
- W2991541566 cites W1972433470 @default.
- W2991541566 cites W1974759530 @default.
- W2991541566 cites W1974998836 @default.
- W2991541566 cites W1977026584 @default.
- W2991541566 cites W1978597334 @default.
- W2991541566 cites W1980297985 @default.
- W2991541566 cites W1981679795 @default.
- W2991541566 cites W1981727048 @default.
- W2991541566 cites W1981768163 @default.
- W2991541566 cites W1983846706 @default.
- W2991541566 cites W1984200333 @default.
- W2991541566 cites W1984317770 @default.
- W2991541566 cites W1984829162 @default.
- W2991541566 cites W1984869489 @default.
- W2991541566 cites W1985090985 @default.
- W2991541566 cites W1985661446 @default.
- W2991541566 cites W1987173107 @default.
- W2991541566 cites W1989353122 @default.
- W2991541566 cites W1989532264 @default.
- W2991541566 cites W1990581514 @default.
- W2991541566 cites W1990819828 @default.
- W2991541566 cites W1991576933 @default.
- W2991541566 cites W1992222970 @default.
- W2991541566 cites W1994317728 @default.
- W2991541566 cites W1994606166 @default.
- W2991541566 cites W1995370658 @default.
- W2991541566 cites W1996402667 @default.
- W2991541566 cites W1996987711 @default.
- W2991541566 cites W1997082113 @default.
- W2991541566 cites W1998294971 @default.
- W2991541566 cites W1998335883 @default.
- W2991541566 cites W1998593984 @default.
- W2991541566 cites W1999452940 @default.
- W2991541566 cites W1999630081 @default.
- W2991541566 cites W1999827951 @default.
- W2991541566 cites W2000304313 @default.
- W2991541566 cites W2000312218 @default.
- W2991541566 cites W2000763730 @default.
- W2991541566 cites W2001195560 @default.
- W2991541566 cites W2002889549 @default.
- W2991541566 cites W2003339289 @default.
- W2991541566 cites W2004201085 @default.
- W2991541566 cites W2004972822 @default.
- W2991541566 cites W2006943025 @default.
- W2991541566 cites W2007081516 @default.
- W2991541566 cites W2007977381 @default.
- W2991541566 cites W2008508054 @default.
- W2991541566 cites W2009006708 @default.
- W2991541566 cites W2009717643 @default.
- W2991541566 cites W2010920096 @default.
- W2991541566 cites W2011577003 @default.
- W2991541566 cites W2012206046 @default.
- W2991541566 cites W2012639577 @default.
- W2991541566 cites W2012952905 @default.
- W2991541566 cites W2013023010 @default.
- W2991541566 cites W2013720553 @default.
- W2991541566 cites W2013940388 @default.
- W2991541566 cites W2014497513 @default.
- W2991541566 cites W2015241097 @default.
- W2991541566 cites W2016126067 @default.
- W2991541566 cites W2017255572 @default.
- W2991541566 cites W2018040130 @default.