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- W2991551644 abstract "Abstract The aim of this study is to determine effects of surface treatment on coated-carbonate apatite (CO 3 Ap) scaffold using silane coupling agent of 3-(trimethoxysilyl) propyl methacrylate. The effect of coating properties with and without surface treatment were investigated through in vitro bioactivity and biocompatibility. Firstly, CO3Ap scaffold was fabricated by transforming β-TCP scaffold via hydrothermal treatment. CO 3 Ap scaffolds were treated in 2% silane solution before coating in chitosan solution (0.5%, 1% and 2%) by dipping method. The coated scaffold without silane treatment denoted as UTR while with silane treatment denoted as TR. It was found that, the presence of Si-OH group enhanced apatite growth on the coated scaffold. TR0.5 has capability to induce apatite growth for 7 days immersion in HBSS compared to UTR0.5. Rougher surface and different surface charge properties have influenced cell viability on the coated CO 3 Ap scaffold. To be concluded, it is important to note that bioactivity and cell activity were forced by surface energy or topography, composition and electrostatic interaction." @default.
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- W2991551644 date "2019-11-01" @default.
- W2991551644 modified "2023-10-16" @default.
- W2991551644 title "Silane treatment of coated carbonate apatite scaffold affects bioactivity and cell viability" @default.
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- W2991551644 doi "https://doi.org/10.1088/1742-6596/1372/1/012054" @default.
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