FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2991602861> ?p ?o ?g. }

• W2991602861 endingPage "e18041" @default.
• W2991602861 startingPage "e18041" @default.
• W2991602861 abstract "Fetal chromosomal abnormalities are considered to be the main cause of spontaneous abortion (SA). We aimed to determine the differences in the rates and numbers of chromosomal abnormalities between samples from women with a history of one versus more than one SA as well as between samples from first- and second-trimester SAs in women from Northeast China.In total, 1210 products of conception (POCs) from patients with a history of one or more SAs were examined. Of these 1210 samples, 434 were from women with a history of 1 SA, and 776 were from women with a history of more than 1 SA. Additionally, 1071 samples were from the first trimester, 118 were from the second trimester, and 21 were from the third trimester. We identified chromosomal abnormalities by next-generation sequencing (NGS) technology. Among the 1210 POCs in women with SA, 607 (50.17%) had fetal chromosomal abnormalities. There were no significant differences in the rates of chromosomal abnormalities according to the abortion frequency. However, first-trimester SA had a significantly higher percentage of fetal chromosomal abnormalities than second-trimester SA (P < .05). Among 663 chromosomal abnormalities, 633 abnormalities occurred in first-trimester SA; the most frequent karyotype was trisomy 16 (14.38%), followed by monosomy X (13.27%), trisomy 22 (7.90%), and trisomy 15 (5.37%). Thirty abnormalities occurred in second-trimester SA; the most frequent karyotype was trisomy 18 (26.67%), followed by monosomy X (16.67%), trisomy 21 (13.33%), and trisomy 13 (10.00%). No chromosomal abnormalities occurred in the third trimester.These findings indicate the importance of determining the genetic cause of abortion in patients with a history of SA. We also identified a trend suggesting that the percentage of fetal chromosomal abnormalities is significantly higher in first- than second-trimester SA. The detection rate of chromosomal abnormalities in POCs from SA can be increased by NGS, which is beneficial for couples with recurrent miscarriages and offers better genetic counseling in the clinical setting." @default.
• W2991602861 created "2019-12-05" @default.
• W2991602861 creator A5022290210 @default.
• W2991602861 creator A5028043625 @default.
• W2991602861 creator A5036681067 @default.
• W2991602861 creator A5040327154 @default.
• W2991602861 creator A5055850984 @default.
• W2991602861 creator A5062800963 @default.
• W2991602861 creator A5076077804 @default.
• W2991602861 date "2019-11-01" @default.
• W2991602861 modified "2023-10-18" @default.
• W2991602861 title "Chromosomal copy number variations in products of conception from spontaneous abortion by next-generation sequencing technology" @default.
• W2991602861 cites W1969495490 @default.
• W2991602861 cites W1976089365 @default.
• W2991602861 cites W1979923278 @default.
• W2991602861 cites W2002776039 @default.
• W2991602861 cites W2011238217 @default.
• W2991602861 cites W2015161517 @default.
• W2991602861 cites W2033518280 @default.
• W2991602861 cites W2072295794 @default.
• W2991602861 cites W2073005651 @default.
• W2991602861 cites W2073923672 @default.
• W2991602861 cites W2110657082 @default.
• W2991602861 cites W2127029849 @default.
• W2991602861 cites W2144967747 @default.
• W2991602861 cites W2219585336 @default.
• W2991602861 cites W2253160634 @default.
• W2991602861 cites W2338458948 @default.
• W2991602861 cites W2594530966 @default.
• W2991602861 cites W2612557787 @default.
• W2991602861 cites W2789251570 @default.
• W2991602861 cites W2910583407 @default.
• W2991602861 cites W4211211389 @default.
• W2991602861 doi "https://doi.org/10.1097/md.0000000000018041" @default.
• W2991602861 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6882649" @default.
• W2991602861 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31764825" @default.
• W2991602861 hasPublicationYear "2019" @default.
• W2991602861 type Work @default.
• W2991602861 sameAs 2991602861 @default.
• W2991602861 citedByCount "14" @default.
• W2991602861 countsByYear W29916028612020 @default.
• W2991602861 countsByYear W29916028612021 @default.
• W2991602861 countsByYear W29916028612022 @default.
• W2991602861 countsByYear W29916028612023 @default.
• W2991602861 crossrefType "journal-article" @default.
• W2991602861 hasAuthorship W2991602861A5022290210 @default.
• W2991602861 hasAuthorship W2991602861A5028043625 @default.
• W2991602861 hasAuthorship W2991602861A5036681067 @default.
• W2991602861 hasAuthorship W2991602861A5040327154 @default.
• W2991602861 hasAuthorship W2991602861A5055850984 @default.
• W2991602861 hasAuthorship W2991602861A5062800963 @default.
• W2991602861 hasAuthorship W2991602861A5076077804 @default.
• W2991602861 hasBestOaLocation W29916028611 @default.
• W2991602861 hasConcept C104317684 @default.
• W2991602861 hasConcept C118552586 @default.
• W2991602861 hasConcept C131872663 @default.
• W2991602861 hasConcept C172680121 @default.
• W2991602861 hasConcept C2776229224 @default.
• W2991602861 hasConcept C2778642596 @default.
• W2991602861 hasConcept C2779142324 @default.
• W2991602861 hasConcept C2779234561 @default.
• W2991602861 hasConcept C2779672484 @default.
• W2991602861 hasConcept C2779954681 @default.
• W2991602861 hasConcept C2780343435 @default.
• W2991602861 hasConcept C29456083 @default.
• W2991602861 hasConcept C3019714739 @default.
• W2991602861 hasConcept C30481170 @default.
• W2991602861 hasConcept C53226629 @default.
• W2991602861 hasConcept C54355233 @default.
• W2991602861 hasConcept C71924100 @default.
• W2991602861 hasConcept C86803240 @default.
• W2991602861 hasConceptScore W2991602861C104317684 @default.
• W2991602861 hasConceptScore W2991602861C118552586 @default.
• W2991602861 hasConceptScore W2991602861C131872663 @default.
• W2991602861 hasConceptScore W2991602861C172680121 @default.
• W2991602861 hasConceptScore W2991602861C2776229224 @default.
• W2991602861 hasConceptScore W2991602861C2778642596 @default.
• W2991602861 hasConceptScore W2991602861C2779142324 @default.
• W2991602861 hasConceptScore W2991602861C2779234561 @default.
• W2991602861 hasConceptScore W2991602861C2779672484 @default.
• W2991602861 hasConceptScore W2991602861C2779954681 @default.
• W2991602861 hasConceptScore W2991602861C2780343435 @default.
• W2991602861 hasConceptScore W2991602861C29456083 @default.
• W2991602861 hasConceptScore W2991602861C3019714739 @default.
• W2991602861 hasConceptScore W2991602861C30481170 @default.
• W2991602861 hasConceptScore W2991602861C53226629 @default.
• W2991602861 hasConceptScore W2991602861C54355233 @default.
• W2991602861 hasConceptScore W2991602861C71924100 @default.
• W2991602861 hasConceptScore W2991602861C86803240 @default.
• W2991602861 hasIssue "47" @default.
• W2991602861 hasLocation W29916028611 @default.
• W2991602861 hasLocation W29916028612 @default.
• W2991602861 hasLocation W29916028613 @default.
• W2991602861 hasLocation W29916028614 @default.
• W2991602861 hasLocation W29916028615 @default.
• W2991602861 hasOpenAccess W2991602861 @default.
• W2991602861 hasPrimaryLocation W29916028611 @default.
• W2991602861 hasRelatedWork W1539553431 @default.

• next