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- W2991616554 abstract "Bronchiectasis and asthma are airway disorders characterised by airway inflammation. Difficulty clearing mucus from the lungs is a symptom for both disorders resulting in recurrent infective exacerbations, decline in lung function and QOL. To evaluate effects of long-term humidification therapy with high flow air, fully humidified at 37°C in patients with bronchiectasis and patients with bronchiectasis and asthma (overlap). We studied 12 patients (pt), 8 with bronchiectasis and 6 with overlap. Pt, previously underwent conventional rehabilitative treatment, presented more than 3 exacerbations in the previous 6 months and at least 1 hospital admission. At enrolment, diurnal respiratory function (FVC, FEV1, arterial gas analysis) and dyspnoea (6minute walk test, MRC scale) were evaluated. Each patient was proposed a trial with long-term humidification therapy. Pt were instructed to use the treatment for 2 or more hours per day. Pt were re-evaluated after 6 months. The treatment was well tolerated for all pt. No adverse effect was reported. Two bronchiectasis pt and one overlap each presented one exacerbation that resolved in few days ( Our data demonstrate that LTHT decreased number of exacerbations. Significant improvements were also noted in lung function and QOL. More studies are necessary to clarify the clinical utility of this treatment in bronchiectasis patients and patients with overlap" @default.
- W2991616554 created "2019-12-05" @default.
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- W2991616554 date "2019-09-28" @default.
- W2991616554 modified "2023-09-22" @default.
- W2991616554 title "Effects of long-term humidification therapy in bronchiectasis patients and overlap (bronchiectasis/asthma)" @default.
- W2991616554 doi "https://doi.org/10.1183/13993003.congress-2019.pa3973" @default.
- W2991616554 hasPublicationYear "2019" @default.
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