Matches in SemOpenAlex for { <https://semopenalex.org/work/W2991709024> ?p ?o ?g. }
Showing items 1 to 56 of
56
with 100 items per page.
- W2991709024 endingPage "91" @default.
- W2991709024 startingPage "84" @default.
- W2991709024 abstract "The study is aimed at assessing the efficacy and safety of topical carbonic anhydrase inhibitor (IAC--i.e. ophthalmic suspension of brinzolamide 1%--Azopt) in the treatment of corneal edema.For this purpose, we carried out an experimental, epidemiological-operational, randomised, placebo-controlled and double blind study, on three groups of laboratory animals (rabbits): group 1 (5 rabbits) included endothelial corneal injuries inflicted by ultrasound exposure by means of a phacoemulsification sound in both eyes group 2 (5 rabbits) included endothelial corneal injuries inflicted by direct trauma in both eyes group 3 (3 rabbits)--no endothelial corneal lesions (control group) In each group we instilled, all the animals, with ophthalmic suspension of brinzolamide 1% (Azopt), 1 drop t.i.d., in one eye for 14 days (starting the following day after infliction of endothelial injuries, when the corneal edema was evidenced by biomicroscopic examination) and placebo (saline solution 0.9% with the same osmolar and pH values as the Azopt) in the other eye. The assessment was performed throughout the following stages: To: preceding the infliction of corneal endothelial injuries, resorting to: biomicroscopic examination ultrasound pahimetry direct specular microscopy T1: the following day after infliction of corneal endothelial injuries, resorting to: biomicroscopic examination (the assessment of corneal edema) ultrasound pahimetry (measurement of corneal thickness and, hence edema) direct specular microscopy (cell density and endothelial ultrastructure evaluation: cellular polimegetism, pleiomorphism) T2: in the wake of 14 days therapy (after eye removal), adding to the previous examinations: indirect specular microscopy (with the same aim as the direct examination, yet examination carried out from the endothelial side) pathologic examination (using hematoxilin-eosin dye and Van-Gieson dye)." @default.
- W2991709024 created "2019-12-13" @default.
- W2991709024 creator A5011977039 @default.
- W2991709024 creator A5013185489 @default.
- W2991709024 creator A5031207562 @default.
- W2991709024 creator A5045143292 @default.
- W2991709024 creator A5071735340 @default.
- W2991709024 creator A5091723193 @default.
- W2991709024 date "2002-01-01" @default.
- W2991709024 modified "2023-09-23" @default.
- W2991709024 title "[The role of Brinzolamide 1% ophtalmic suspension in corneal edema]." @default.
- W2991709024 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12723185" @default.
- W2991709024 hasPublicationYear "2002" @default.
- W2991709024 type Work @default.
- W2991709024 sameAs 2991709024 @default.
- W2991709024 citedByCount "0" @default.
- W2991709024 crossrefType "journal-article" @default.
- W2991709024 hasAuthorship W2991709024A5011977039 @default.
- W2991709024 hasAuthorship W2991709024A5013185489 @default.
- W2991709024 hasAuthorship W2991709024A5031207562 @default.
- W2991709024 hasAuthorship W2991709024A5045143292 @default.
- W2991709024 hasAuthorship W2991709024A5071735340 @default.
- W2991709024 hasAuthorship W2991709024A5091723193 @default.
- W2991709024 hasConcept C118487528 @default.
- W2991709024 hasConcept C141071460 @default.
- W2991709024 hasConcept C2775901793 @default.
- W2991709024 hasConcept C2776882836 @default.
- W2991709024 hasConcept C2780886150 @default.
- W2991709024 hasConcept C71924100 @default.
- W2991709024 hasConceptScore W2991709024C118487528 @default.
- W2991709024 hasConceptScore W2991709024C141071460 @default.
- W2991709024 hasConceptScore W2991709024C2775901793 @default.
- W2991709024 hasConceptScore W2991709024C2776882836 @default.
- W2991709024 hasConceptScore W2991709024C2780886150 @default.
- W2991709024 hasConceptScore W2991709024C71924100 @default.
- W2991709024 hasIssue "4" @default.
- W2991709024 hasLocation W29917090241 @default.
- W2991709024 hasOpenAccess W2991709024 @default.
- W2991709024 hasPrimaryLocation W29917090241 @default.
- W2991709024 hasRelatedWork W1976249152 @default.
- W2991709024 hasRelatedWork W2027522840 @default.
- W2991709024 hasRelatedWork W2056651678 @default.
- W2991709024 hasRelatedWork W2076907450 @default.
- W2991709024 hasRelatedWork W2125941238 @default.
- W2991709024 hasRelatedWork W2195557650 @default.
- W2991709024 hasRelatedWork W2380707943 @default.
- W2991709024 hasRelatedWork W3029924527 @default.
- W2991709024 hasRelatedWork W3031397560 @default.
- W2991709024 hasRelatedWork W84452131 @default.
- W2991709024 hasVolume "55" @default.
- W2991709024 isParatext "false" @default.
- W2991709024 isRetracted "false" @default.
- W2991709024 magId "2991709024" @default.
- W2991709024 workType "article" @default.