FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2991924066> ?p ?o ?g. }

• W2991924066 endingPage "2608" @default.
• W2991924066 startingPage "2600" @default.
• W2991924066 abstract "Background & aims Chemoradiation and bioradiation (CRT/BRT) for locally advanced head and neck squamous cell carcinoma (LAHNSCC) often comes with high toxicity rates, interfering with oral intake and leading to temporary tube feeding (TF) dependency. High-quality scientific evidence for indicators of prophylactic gastrostomy insertion is not available. The aim of this retrospective cohort study was to develop a prediction model to identify patients who need prophylactic gastrostomy insertion, defined as the expected use of TF for at least four weeks. Methods Four-hundred-fifty LAHNSCC patients receiving CRT/BRT with curative intent between 2013 and 2016 were included in the study. Primary outcome was TF-dependency for four weeks or longer. Patient, tumor, and treatment characteristics were extracted from the medical records and their effects on the use of TF were analyzed using univariable and multivariable analysis. The prediction model was internally validated using bootstrapping techniques. Results Sixty-five percent (294/450 patients) required TF for four weeks or longer. Variables included in the model were: body mass index and adjusted diet at start of CRT/BRT, percentage weight change at baseline, World Health Organization performance status, tumor subsite, TNM-classification, CRT/BRT, mean radiation dose on the contralateral submandibular and parotid gland. The corrected Area Under the Curve after internal validation was 72.3%, indicating good discriminative properties of the prediction model. Conclusions We developed and internally validated a prediction model that is intended to estimate TF-dependency for at least four weeks in LAHNSCC patients treated with CRT/BRT. This model can be used as a tool to support personalized decision making on prophylactic gastrostomy insertion." @default.
• W2991924066 created "2019-12-13" @default.
• W2991924066 creator A5009217884 @default.
• W2991924066 creator A5013717261 @default.
• W2991924066 creator A5015424682 @default.
• W2991924066 creator A5024997306 @default.
• W2991924066 creator A5034998501 @default.
• W2991924066 creator A5047802794 @default.
• W2991924066 creator A5051610674 @default.
• W2991924066 creator A5054152509 @default.
• W2991924066 creator A5084733864 @default.
• W2991924066 creator A5087173002 @default.
• W2991924066 creator A5089106956 @default.
• W2991924066 date "2020-08-01" @default.
• W2991924066 modified "2023-10-13" @default.
• W2991924066 title "Prediction model for tube feeding dependency during chemoradiotherapy for at least four weeks in head and neck cancer patients: A tool for prophylactic gastrostomy decision making" @default.
• W2991924066 cites W1541382131 @default.
• W2991924066 cites W1920887326 @default.
• W2991924066 cites W1965981843 @default.
• W2991924066 cites W1967208836 @default.
• W2991924066 cites W1983667491 @default.
• W2991924066 cites W1985213644 @default.
• W2991924066 cites W1993095302 @default.
• W2991924066 cites W1993272560 @default.
• W2991924066 cites W1995383543 @default.
• W2991924066 cites W1995808524 @default.
• W2991924066 cites W2012645265 @default.
• W2991924066 cites W2015375887 @default.
• W2991924066 cites W2017238314 @default.
• W2991924066 cites W2019790627 @default.
• W2991924066 cites W2024245686 @default.
• W2991924066 cites W2028235794 @default.
• W2991924066 cites W2037668591 @default.
• W2991924066 cites W2040170417 @default.
• W2991924066 cites W2042979299 @default.
• W2991924066 cites W2043453187 @default.
• W2991924066 cites W2056459938 @default.
• W2991924066 cites W2071858069 @default.
• W2991924066 cites W2079633493 @default.
• W2991924066 cites W2085503214 @default.
• W2991924066 cites W2089201754 @default.
• W2991924066 cites W2089257078 @default.
• W2991924066 cites W2090186540 @default.
• W2991924066 cites W2091406619 @default.
• W2991924066 cites W2095688437 @default.
• W2991924066 cites W2102676339 @default.
• W2991924066 cites W2116931764 @default.
• W2991924066 cites W2117461158 @default.
• W2991924066 cites W2118829544 @default.
• W2991924066 cites W2124047443 @default.
• W2991924066 cites W2130682755 @default.
• W2991924066 cites W2146404132 @default.
• W2991924066 cites W2151730005 @default.
• W2991924066 cites W2153340330 @default.
• W2991924066 cites W2153545068 @default.
• W2991924066 cites W2155384808 @default.
• W2991924066 cites W2169659822 @default.
• W2991924066 cites W2171929115 @default.
• W2991924066 cites W2237532463 @default.
• W2991924066 cites W2275631374 @default.
• W2991924066 cites W2335476237 @default.
• W2991924066 cites W2342982428 @default.
• W2991924066 cites W2411293912 @default.
• W2991924066 cites W2472774105 @default.
• W2991924066 cites W2484447047 @default.
• W2991924066 cites W2545039023 @default.
• W2991924066 cites W2581045991 @default.
• W2991924066 cites W2582416687 @default.
• W2991924066 cites W2589355963 @default.
• W2991924066 cites W2601971996 @default.
• W2991924066 cites W2736943218 @default.
• W2991924066 cites W2738757519 @default.
• W2991924066 cites W2741358081 @default.
• W2991924066 cites W2808720242 @default.
• W2991924066 cites W2894839831 @default.
• W2991924066 cites W2905086874 @default.
• W2991924066 cites W4236026420 @default.
• W2991924066 doi "https://doi.org/10.1016/j.clnu.2019.11.033" @default.
• W2991924066 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31839429" @default.
• W2991924066 hasPublicationYear "2020" @default.
• W2991924066 type Work @default.
• W2991924066 sameAs 2991924066 @default.
• W2991924066 citedByCount "14" @default.
• W2991924066 countsByYear W29919240662020 @default.
• W2991924066 countsByYear W29919240662021 @default.
• W2991924066 countsByYear W29919240662022 @default.
• W2991924066 countsByYear W29919240662023 @default.
• W2991924066 crossrefType "journal-article" @default.
• W2991924066 hasAuthorship W2991924066A5009217884 @default.
• W2991924066 hasAuthorship W2991924066A5013717261 @default.
• W2991924066 hasAuthorship W2991924066A5015424682 @default.
• W2991924066 hasAuthorship W2991924066A5024997306 @default.
• W2991924066 hasAuthorship W2991924066A5034998501 @default.
• W2991924066 hasAuthorship W2991924066A5047802794 @default.
• W2991924066 hasAuthorship W2991924066A5051610674 @default.
• W2991924066 hasAuthorship W2991924066A5054152509 @default.
• W2991924066 hasAuthorship W2991924066A5084733864 @default.
• W2991924066 hasAuthorship W2991924066A5087173002 @default.

• next