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• W2992415883 endingPage "113762" @default.
• W2992415883 startingPage "113762" @default.
• W2992415883 abstract "One emerging problem that recently has become a vastly acknowledged topic of concern is the environmental contamination by pharmaceuticals. Diclofenac (DCF) is one of the most common pharmaceuticals found, due to its high utilization and low removal rate in wastewater treatment processes. In this work, Solanum lycopersicum L. was used as a model to unravel how DCF contamination can affect crops, focusing on the internal mechanisms triggered by this exposure. For this purpose, plants were exposed to two different DCF concentrations (0.5 mg L−1 and 5 mg L−1). Results obtained here point towards a loss of shoot performance when plants were exposed to very high concentrations of DCF, but no delay or loss of yield in the flowering and fruit stages were ascribed to DCF contamination. Our data shows that a state of oxidative stress due to high reactive oxygen species accumulation was associated with this contamination, with very high DCF levels leading to a rise of lipid peroxidation, possibly accentuated by the inhibition of ROS-scavenging enzymes and unable to be counteracted by the visible upregulation of proline and the thiol-based redox network. Overall, these results allow to infer that in the current environmental context, no noticeable negative effects should be associated with the presence of DCF in soils where this crop is cultivated. However, the oxidative stress and lower biomass associated with the highest concentration are alarming, since DCF levels in the environment are continuously increasing and further measures are necessary to assess this problematic." @default.
• W2992415883 created "2019-12-13" @default.
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• W2992415883 date "2020-03-01" @default.
• W2992415883 modified "2023-09-26" @default.
• W2992415883 title "Response of Solanum lycopersicum L. to diclofenac – Impacts on the plant’s antioxidant mechanisms" @default.
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• W2992415883 doi "https://doi.org/10.1016/j.envpol.2019.113762" @default.
• W2992415883 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31864077" @default.
• W2992415883 hasPublicationYear "2020" @default.
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