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- W2992519998 abstract "Stress ulcer or stress related mucosal disease (SRMD) is animportant cause of morbidity and mortality in intensive care units. No drug prophylaxis for SRMDincrease the rate of morbidity and mortality. Unnecessary use of drugs results in adverse drug reactionsand impose additional costs. The purpose of this study was to investigate the medications used for stressulcer prophylaxis in pediatric intensive care unit (PICU) in Sari Bu-Ali Sina Hospital.Materials and methods: This cross-sectional study was done in PICU patients who receivedstress ulcer prophylaxis during 2014. Data and physiologic parameters related to stress ulcer prophylacticdrugs, the dosage, dosing interval, and duration of medications were recorded. SPSS16 was used for dataanalyses.Results: Stress ulcer prophylactic drugs were used in 40 patients of all 78 cases and ranitidine was themost commonly used drug (85%). The most frequent indication to prescribe these drugs were sepsis(20%), NPO (nothing per oral) with seizure (20%), NPO (15%), intubation (12.5%), and coagulopathy(7.5%). According to the guidelines, stress ulcer prophylactic drugs were correctly prescribed only in42.5% of the patients.Conclusion: In this study, most of the cases received stress ulcer prophylactic drugs with no trueindication. Therefore, more practical notice is needed to act according the guidelines for reducing theunnecessary administration of medication." @default.
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- W2992519998 date "2016-03-15" @default.
- W2992519998 modified "2023-09-25" @default.
- W2992519998 title "|Evaluation of PICU Stress Ulcer Prophylaxis in Sari Bu-Ali Sina Hospital" @default.
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