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- W2992912683 abstract "BACKGROUND Nanosecond pulsed electric field technology (also known as Nano-Pulse Stimulation or NPS) is a nonthermal, drug-free, energy-based technology that has demonstrated effects on cellular structures of the dermis and epidermis in previous clinical studies. OBJECTIVE To evaluate the safety and efficacy of a single NPS treatment for clearing seborrheic keratoses (SKs). MATERIALS AND METHODS This study was a prospective, randomized, open-label, multisite, nonsignificant risk trial in which each subject served as their own control. Fifty-eight subjects had 3 of 4 confirmed SK lesions treated, resulting in 174 total treated lesions. Subjects returned for 5 to 6 follow-up evaluations and photographs. RESULTS At 106 days after NPS treatment, 82% of treated seborrheic keratoses were rated clear or mostly clear by the assessing physician. Seventy-one percent of lesions were rated clear or mostly clear by the 3 independent reviewers based on the 106-day photographs. All treated subjects returned for all study visits, and 78% of the subjects were satisfied or mostly satisfied with the outcome of the treatment. No adverse events were reported. CONCLUSION The NPS procedure was well tolerated and effective in the removal of SKs." @default.
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- W2992912683 date "2019-12-04" @default.
- W2992912683 modified "2023-09-27" @default.
- W2992912683 title "Safety and Efficacy of Nanosecond Pulsed Electric Field Treatment of Seborrheic Keratoses" @default.
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- W2992912683 doi "https://doi.org/10.1097/dss.0000000000002278" @default.
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