FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2993006944> ?p ?o ?g. }

• W2993006944 abstract "The adaptive immune system of vertebrates can detect, respond to, and memorize diverse pathogens from past experience. While the clonal selection of T helper (Th) cells is the simple and established mechanism to better recognize new pathogens, the question that still remains unexplored is how the Th cells can acquire better ways to bias the responses of immune cells for eliminating pathogens more efficiently by translating the recognized antigen information into regulatory signals. In this work, we address this problem by associating the adaptive immune network organized by the Th cells with reinforcement learning (RL). By employing recent advancements of network-based RL, we show that the Th immune network can acquire the association between antigen patterns of and the effective responses to pathogens. Moreover, the clonal selection as well as other inter-cellular interactions are derived as a learning rule of the network. We also demonstrate that the stationary clone-size distribution after learning shares characteristic features with those observed experimentally. Our theoretical framework may contribute to revising and renewing our understanding of adaptive immunity as a learning system." @default.
• W2993006944 created "2019-12-13" @default.
• W2993006944 creator A5006202308 @default.
• W2993006944 creator A5087813809 @default.
• W2993006944 date "2021-03-09" @default.
• W2993006944 modified "2023-10-18" @default.
• W2993006944 title "Understanding adaptive immune system as reinforcement learning" @default.
• W2993006944 cites W1268882458 @default.
• W2993006944 cites W1520434148 @default.
• W2993006944 cites W1972640719 @default.
• W2993006944 cites W1977164923 @default.
• W2993006944 cites W1978297432 @default.
• W2993006944 cites W1985185356 @default.
• W2993006944 cites W1985580675 @default.
• W2993006944 cites W1993763272 @default.
• W2993006944 cites W1996174406 @default.
• W2993006944 cites W1997632704 @default.
• W2993006944 cites W2003642939 @default.
• W2993006944 cites W2024748688 @default.
• W2993006944 cites W2029495614 @default.
• W2993006944 cites W2043416239 @default.
• W2993006944 cites W2046308122 @default.
• W2993006944 cites W2049026112 @default.
• W2993006944 cites W2049886753 @default.
• W2993006944 cites W2061000745 @default.
• W2993006944 cites W2066930665 @default.
• W2993006944 cites W2078253933 @default.
• W2993006944 cites W2101504692 @default.
• W2993006944 cites W2124015941 @default.
• W2993006944 cites W2130473166 @default.
• W2993006944 cites W2136499612 @default.
• W2993006944 cites W2137055925 @default.
• W2993006944 cites W2164015638 @default.
• W2993006944 cites W2173617309 @default.
• W2993006944 cites W2233660390 @default.
• W2993006944 cites W2235876070 @default.
• W2993006944 cites W2257979135 @default.
• W2993006944 cites W2557705992 @default.
• W2993006944 cites W2578885448 @default.
• W2993006944 cites W2594694689 @default.
• W2993006944 cites W2612459567 @default.
• W2993006944 cites W2670890989 @default.
• W2993006944 cites W2738724892 @default.
• W2993006944 cites W2763756177 @default.
• W2993006944 cites W2800666856 @default.
• W2993006944 cites W2807786681 @default.
• W2993006944 cites W2808009702 @default.
• W2993006944 cites W2884116101 @default.
• W2993006944 cites W2884277124 @default.
• W2993006944 cites W2887382620 @default.
• W2993006944 cites W2889980427 @default.
• W2993006944 cites W2894849296 @default.
• W2993006944 cites W2896667872 @default.
• W2993006944 cites W2922185282 @default.
• W2993006944 cites W2964241261 @default.
• W2993006944 cites W3102088880 @default.
• W2993006944 cites W4235608162 @default.
• W2993006944 cites W4246233237 @default.
• W2993006944 hasPublicationYear "2021" @default.
• W2993006944 type Work @default.
• W2993006944 sameAs 2993006944 @default.
• W2993006944 citedByCount "0" @default.
• W2993006944 crossrefType "journal-article" @default.
• W2993006944 hasAuthorship W2993006944A5006202308 @default.
• W2993006944 hasAuthorship W2993006944A5087813809 @default.
• W2993006944 hasBestOaLocation W29930069441 @default.
• W2993006944 hasConcept C104317684 @default.
• W2993006944 hasConcept C111472728 @default.
• W2993006944 hasConcept C125014702 @default.
• W2993006944 hasConcept C138885662 @default.
• W2993006944 hasConcept C145420912 @default.
• W2993006944 hasConcept C154945302 @default.
• W2993006944 hasConcept C15744967 @default.
• W2993006944 hasConcept C169760540 @default.
• W2993006944 hasConcept C193419808 @default.
• W2993006944 hasConcept C203014093 @default.
• W2993006944 hasConcept C2776954793 @default.
• W2993006944 hasConcept C30038468 @default.
• W2993006944 hasConcept C41008148 @default.
• W2993006944 hasConcept C54355233 @default.
• W2993006944 hasConcept C81089528 @default.
• W2993006944 hasConcept C81917197 @default.
• W2993006944 hasConcept C86803240 @default.
• W2993006944 hasConcept C8891405 @default.
• W2993006944 hasConcept C89611455 @default.
• W2993006944 hasConcept C97541855 @default.
• W2993006944 hasConceptScore W2993006944C104317684 @default.
• W2993006944 hasConceptScore W2993006944C111472728 @default.
• W2993006944 hasConceptScore W2993006944C125014702 @default.
• W2993006944 hasConceptScore W2993006944C138885662 @default.
• W2993006944 hasConceptScore W2993006944C145420912 @default.
• W2993006944 hasConceptScore W2993006944C154945302 @default.
• W2993006944 hasConceptScore W2993006944C15744967 @default.
• W2993006944 hasConceptScore W2993006944C169760540 @default.
• W2993006944 hasConceptScore W2993006944C193419808 @default.
• W2993006944 hasConceptScore W2993006944C203014093 @default.
• W2993006944 hasConceptScore W2993006944C2776954793 @default.
• W2993006944 hasConceptScore W2993006944C30038468 @default.
• W2993006944 hasConceptScore W2993006944C41008148 @default.
• W2993006944 hasConceptScore W2993006944C54355233 @default.

• next