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- W2993192496 abstract "Self-assembled peptides possess distinct structural characterizations,inducing the formation of a stable supermolecule with a cavity.This central cavity was employed as drug carrier in last decade.The wide range utilities of self-assembled peptides covered the improved bioavailability,drug targeting release,cytotoxic alleviation,cell penetration activity and so on.There are two kinds of self-assembled peptide generally.One is based on the spatial structure of the peptide,and the other one is based on peptide amphiphile.Amphiphilic peptide has four rationally designed chemical entities.By reasonable controlling the chemical structure,amphiphilic peptides can self-assemble into a variety of nanostructures,such as nanofiber,nanotube,nanoparticles and hydrogel.It is highlighted a kind of peptide that is cellular penetration peptide(CPP).The mechanism of supermolecule formation and drug loading procedures was summarized.The remarkable functions of self-assembled peptides spread a prosperous scene in drug controlled release and drug sustained release." @default.
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- W2993192496 date "2013-08-25" @default.
- W2993192496 modified "2023-09-25" @default.
- W2993192496 title "Utility of the Self-assembling Peptides as Novel Drug Formulations" @default.
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