Matches in SemOpenAlex for { <https://semopenalex.org/work/W2993270319> ?p ?o ?g. }
- W2993270319 endingPage "560" @default.
- W2993270319 startingPage "553" @default.
- W2993270319 abstract "Deoxynivalenol (DON) is a mycotoxin virulence factor that promotes growth of the Fusarium graminearum fungus in wheat floral tissues. To further our understanding of the effects of DON exposure on plant cell function, we characterized DON-induced transcriptional changes in wheat spikelets. Four hundred wheat genes were differentially expressed during infection with wild-type F. graminearum as compared with a Δtri5 mutant strain that is unable to produce DON. Most of these genes were more induced by the DON-producing strain and included genes involved in secondary metabolism, signaling, transport, and stress responses. DON induction was confirmed for a subset of the genes, including TaNFXL1, by treating tissues with DON directly. Previous work indicates that the NFXL1 ortholog represses trichothecene-induced defense responses and bacterial resistance in Arabidopsis, but the role of the NFXL family has not been studied in wheat. We observed greater DON-induced TaNFXL1 gene expression in a susceptible wheat genotype relative to the F. graminearum–resistant genotype Wuhan 1. Functional testing using both virus-induced gene silencing and CRISPR-mediated genome editing indicated that TaNFXL1 represses F. graminearum resistance. Together, this suggests that targeting the TaNFXL1 gene may help to develop disease resistance in cultivated wheat." @default.
- W2993270319 created "2019-12-13" @default.
- W2993270319 creator A5011154726 @default.
- W2993270319 creator A5051920592 @default.
- W2993270319 creator A5053251026 @default.
- W2993270319 creator A5057072705 @default.
- W2993270319 creator A5063175531 @default.
- W2993270319 creator A5075635853 @default.
- W2993270319 creator A5080996637 @default.
- W2993270319 date "2020-03-01" @default.
- W2993270319 modified "2023-10-01" @default.
- W2993270319 title "Genome Editing of a Deoxynivalenol-Induced Transcription Factor Confers Resistance to <i>Fusarium graminearum</i> in Wheat" @default.
- W2993270319 cites W1590206291 @default.
- W2993270319 cites W1802263562 @default.
- W2993270319 cites W1932197330 @default.
- W2993270319 cites W1932214661 @default.
- W2993270319 cites W1981324924 @default.
- W2993270319 cites W1998793813 @default.
- W2993270319 cites W2000046950 @default.
- W2993270319 cites W2003514926 @default.
- W2993270319 cites W2014286854 @default.
- W2993270319 cites W2018051098 @default.
- W2993270319 cites W2026273381 @default.
- W2993270319 cites W2045073208 @default.
- W2993270319 cites W2049417555 @default.
- W2993270319 cites W2056937331 @default.
- W2993270319 cites W2057212520 @default.
- W2993270319 cites W2060933632 @default.
- W2993270319 cites W2065309968 @default.
- W2993270319 cites W2067059594 @default.
- W2993270319 cites W2070969294 @default.
- W2993270319 cites W2076690743 @default.
- W2993270319 cites W2100010691 @default.
- W2993270319 cites W2103953745 @default.
- W2993270319 cites W2105651957 @default.
- W2993270319 cites W2106636872 @default.
- W2993270319 cites W2109972881 @default.
- W2993270319 cites W2117975688 @default.
- W2993270319 cites W2125130217 @default.
- W2993270319 cites W2129178916 @default.
- W2993270319 cites W2141039323 @default.
- W2993270319 cites W2141746586 @default.
- W2993270319 cites W2147655174 @default.
- W2993270319 cites W2158121967 @default.
- W2993270319 cites W2162944901 @default.
- W2993270319 cites W2175951462 @default.
- W2993270319 cites W2251287751 @default.
- W2993270319 cites W2419495057 @default.
- W2993270319 cites W2474913350 @default.
- W2993270319 cites W2536270941 @default.
- W2993270319 cites W2606664525 @default.
- W2993270319 cites W2784100363 @default.
- W2993270319 cites W2787269952 @default.
- W2993270319 cites W2885825048 @default.
- W2993270319 cites W2889411089 @default.
- W2993270319 cites W2890719480 @default.
- W2993270319 cites W2897848663 @default.
- W2993270319 cites W2899950946 @default.
- W2993270319 cites W2901711982 @default.
- W2993270319 cites W2916949596 @default.
- W2993270319 cites W2939198915 @default.
- W2993270319 cites W2951532178 @default.
- W2993270319 cites W2951787366 @default.
- W2993270319 cites W2982095232 @default.
- W2993270319 cites W344253813 @default.
- W2993270319 cites W2096022799 @default.
- W2993270319 doi "https://doi.org/10.1094/mpmi-11-19-0332-r" @default.
- W2993270319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31790345" @default.
- W2993270319 hasPublicationYear "2020" @default.
- W2993270319 type Work @default.
- W2993270319 sameAs 2993270319 @default.
- W2993270319 citedByCount "43" @default.
- W2993270319 countsByYear W29932703192020 @default.
- W2993270319 countsByYear W29932703192021 @default.
- W2993270319 countsByYear W29932703192022 @default.
- W2993270319 countsByYear W29932703192023 @default.
- W2993270319 crossrefType "journal-article" @default.
- W2993270319 hasAuthorship W2993270319A5011154726 @default.
- W2993270319 hasAuthorship W2993270319A5051920592 @default.
- W2993270319 hasAuthorship W2993270319A5053251026 @default.
- W2993270319 hasAuthorship W2993270319A5057072705 @default.
- W2993270319 hasAuthorship W2993270319A5063175531 @default.
- W2993270319 hasAuthorship W2993270319A5075635853 @default.
- W2993270319 hasAuthorship W2993270319A5080996637 @default.
- W2993270319 hasBestOaLocation W29932703191 @default.
- W2993270319 hasConcept C104317684 @default.
- W2993270319 hasConcept C119056186 @default.
- W2993270319 hasConcept C135763542 @default.
- W2993270319 hasConcept C141231307 @default.
- W2993270319 hasConcept C143065580 @default.
- W2993270319 hasConcept C150194340 @default.
- W2993270319 hasConcept C2776889654 @default.
- W2993270319 hasConcept C2778867309 @default.
- W2993270319 hasConcept C54355233 @default.
- W2993270319 hasConcept C59822182 @default.
- W2993270319 hasConcept C60987743 @default.
- W2993270319 hasConcept C84699730 @default.
- W2993270319 hasConcept C86803240 @default.