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- W2993367992 abstract "From the Solid Tumor Service, Department of Medicine, the Department of Biostatistics, the Urology Service, the Department of Surgery, and the Department of Biochemistry, Memorial Sloan-Kettering Cancer Center, New York, New York. This study was supported in part by National Cancer Institute Grant and Contracts CA-05826. CA-08748, NO&CM-07337, NOl-CM57043, and by American Cancer Society Fellowship A-437. Dr. Bosf is a Junior Clinical Faculty Fellow of the American Cancer Society. Requests for reprints should be addressed to Dr. George J. Bosl, Department of Medicine, Solid Tumor Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021. Manuscript accepted August 31, 1982. The serum values of alphafetoprotein, human chorionic gonadotropin, lactate dehydrogenase, and carcinoembryonic antigen in patients with matastatic testicular cancer were revtewed for the period 1972 to 1982. Ail values were obtained before chemotherapy was begun. Elevated values of alphafetoprotein were present in 47 percent of patients tested, of human chorionic gonadotropin in 60 percent, of lactate dehydrogenase in 64 percent, and of carcinoembryonic antigen in 11 percent. The frequency of elevated values of alphafetoprotein, human chorionic gonadotropin, and lactate dehydrogenase decreased during the study period. Inverse reiations between elevated values of alphafetoprotein, human chorionlc gonadotropin, and tactate dehydrogenase and both complete remission rate and survival rate were noted in some of the chemotherapy trials. Carcinoembryonic antigen was beiieved not to be useful as a marker in this disease. It is concluded that assays of alphafetoprotein, human chorionic gonadotropin, and lactate dehydrogenase are important both clinically and prognostically in patients with testicular cancer." @default.
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- W2993367992 date "2003-01-01" @default.
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- W2993367992 title "Serum Tumor Markers in Patients with Metastatic Germ Cell Tumors of the Testis A IO-Year Experience" @default.
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