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- W2993908941 abstract "A possible etiologic role of enteroviruses for type 1 diabetes has been researched for 40 years, but evidence to date is inconclusive. This article summarizes new evidence from Cuban research supporting a role for enteroviruses, both in preclinical stages of autoimmune reactions against pancreatic β cells and at clinical onset, in a population with low type 1 diabetes incidence. Possible pathogenetic mechanisms are also discussed, such as acute cytolytic damage and molecular mimicry. Although direct causal effects of enteroviruses in type 1 diabetes are difficult to demonstrate, arguments supporting their role in type 1 diabetes pathogenesis should not be ignored; and confirmation could contribute to development of more effective preventive strategies." @default.
- W2993908941 created "2019-12-13" @default.
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- W2993908941 date "2013-01-01" @default.
- W2993908941 modified "2023-09-27" @default.
- W2993908941 title "Evidence of association between type 1 diabetes and exposure to enterovirus in Cuban children and adolescents" @default.
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- W2993908941 doi "https://doi.org/10.1590/s1555-79602013000100007" @default.
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