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- W2994091833 abstract "Eosinophilic esophagitis (EoE) is an antigen-driven disease associated with a patchy, panesophageal infiltration of eosinophils, mast cells, and T cells. Persistent inflammation triggers dysregulated wound healing that progresses to pathologic tissue remodeling with esophageal rigidity and clinical symptoms of dysphagia and food impactions. 1 Nhu Q.M. Aceves S.S. Tissue remodeling in chronic eosinophilic esophageal inflammation: parallels in asthma and therapeutic perspectives. Front Med (Lausanne). 2017; 4: 128 Crossref PubMed Scopus (25) Google Scholar The most common complaints in adults and teenagers is dysphagia, whereas younger children more commonly have symptoms that mimic gastroesophageal reflux disease, such as vomiting. The disease pathogenesis is similar in children and adults, with higher rates of strictures and endoscopic remodeling in adults, which may be attributable to distinctions in pathogenesis or longer disease duration. The natural history of untreated or therapy unresponsive EoE is stricture formation." @default.
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- W2994091833 date "2020-03-01" @default.
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- W2994091833 title "Unanswered questions in eosinophilic esophagitis" @default.
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- W2994091833 doi "https://doi.org/10.1016/j.anai.2019.12.003" @default.
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