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- W2994172332 abstract "Experimental studies have shown that acetylcysteine is beneficial in preserving kidney function during coronary procedures. However, its role in routine clinical practice is not known.We studied 75 consecutive patients undergoing coronary procedures who received acetylcysteine, and compared them with 56 consecutive similar patients who served as control. All patients had renal dysfunction, and a single operator did all procedures.Patients in the acetylcysteine group had a decrease in serum creatinine of 0.1 +/- 0.3 mg/dl versus a rise of 0.2 +/- 0.6 mg/dl in the control group (P<0.001). When the benefit in the active drug group was correlated with baseline creatinine, it occurred in all patients, regardless of the degree of kidney dysfunction.We conclude that in patients with varying degrees of renal dysfunction who undergo coronary procedures, acetylcysteine should be used in addition to hydration. It should be an accepted clinical practice that should be adopted routinely in the cardiac catheterization laboratory." @default.
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- W2994172332 date "2004-01-01" @default.
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- W2994172332 title "Effectiveness of acetylcysteine on preventing renal dysfunction in patients undergoing coronary procedures." @default.
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