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• W2994270372 endingPage "108546" @default.
• W2994270372 startingPage "108546" @default.
• W2994270372 abstract "Since 2017, a disease that is characterized by spleen necrosis and swelling has emerged in China's main meat duck breeding provinces, this disease generally causes a large number of ducks to develop a poor mental state and either an increase or loss of appetite, as well as potentially resulting in death. Necrosis of spleen in this disease weakens the duck’s immunity, therefore often leading to secondary infection. The net result of this is significant economic loss to China's duck breeding industry. In our previous research, we determined that the pathogen causing this disease is a new variant duck orthoreovirus (N-DRV). Because the morbidity and mortality rates of the isolate were higher than those of the previously reported strains, 180 healthy 1-day-old Cherry Valley ducklings were selected to be artificially infected in order to determine the pathogenicity of the strain. The weight gains of numbers of the infected group were significantly inhibited after they had been inoculated with the virus, which continued to detoxify in the blood and the cloaca. The main target organ of the virus is the spleen, although the virus can also attack the brain, this does not lead to any obvious pathology in this organ. These findings have enriched our understanding of the N-DRV-XT18 virus and have lain the foundation for further study of the pathogenic mechanism of this virus." @default.
• W2994270372 created "2019-12-13" @default.
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• W2994270372 date "2020-03-01" @default.
• W2994270372 modified "2023-09-27" @default.
• W2994270372 title "Pathogenicity of a variant duck orthoreovirus strain in Cherry Valley Ducklings" @default.
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• W2994270372 doi "https://doi.org/10.1016/j.vetmic.2019.108546" @default.
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