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- W2994322578 abstract "TPS9154 Background: Self-rated symptoms contribute to the Quality of Life (QoL) of cancer patients (pts) and impact on prognosis. Behavioural functions are controlled by the circadian timing system (CTS), through a network of molecular clocks that time cellular proliferation and drug metabolism (Lévi et al. ARPT 2010). Chronotherapy aims at the reduction of treatment-related symptoms through the adjustment of chemotherapy delivery to the CTS. Cancer chronotherapy is delivered at home using programmable pumps, and avoids familial and social disruption. Telemedicine tools can provide continuous information on symptoms, behavior, QoL and CTS from non hospitalized pts. Methods: The inCASA platform enables telemonitoring of multiple functions in order to help physicians to detect early warning signals in pt condition at home, and prompt adequate and timely interventions. Our pilot site investigates the clinical relevance of daily teletransmitted self assessed symptoms, body weight and rest-activity circadian rhythm in cancer pts. This system was first well understood and accepted by 14 pts (9 male, 5 female, 43-77 years) at the outpt clinic, then used by 5 pts (4 male, 1 female, 61±13 years) at home daily for 6+ weeks, while receiving chronotherapy. The pilot phase will accrue 30 pts receiving chronotherapy at home from 03/01/2012. Pts will fill in the M.D. Anderson Symptom Inventory scale on a touch-screen device, measure their body weight using a Bluetooth scale and record their circadian rest-activity rhythm using an infrared wrist-watch accelerometer over 6-weeks. The data are transmitted to the platform, then to a web portal with secured access to be daily inspected by the oncology nursing and medical team. The modelling of these continuous records will define alert thresholds for nurse-controlled graded intervention decisions. Conclusion: The assessment criteria set forth for the inCASA solution will address the issues of pt autonomy, CTS entrainment in the pt usual environment, safety of chronotherapy delivery at home and treatment costs. Its use should induce important organisational changes and perception in healthcare professionals." @default.
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- W2994322578 date "2012-05-20" @default.
- W2994322578 modified "2023-09-27" @default.
- W2994322578 title "The European InCASA telecare-telehealth electronic platform (ICT-FP7) for the daily assessment of symptoms, weight, and activity in cancer patients on chronotherapy at home." @default.
- W2994322578 doi "https://doi.org/10.1200/jco.2012.30.15_suppl.tps9154" @default.
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