FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2994390015> ?p ?o ?g. }

• W2994390015 abstract "As a member of apoptosis inhibition gene family, baculoviral IAP repeat containing 5 (BIRC5) protein acts as a survival factor in oncology through multiple ways. There are huge inconsistent results between urinary cancer risk and BIRC5 polymorphisms, so we searched and documented all eligible articles to clear up the mystery with the help of meta-analysis. According to the inclusion and exclusion criteria, we performed an overall search in Web of Science, PubMed, Google Scholar, Medline, CNKI and Wanfang database with pre-set search strategy up to November 2019. Z-test was performed to determine the statistical difference by Odds ratios (ORs) and 95% confidence intervals (CIs). The stability of the pooled ORs was conducted by one-way sensitivity analyses, Begg's funnel plots and Egger's test were employed to access the potential publication bias. The relationship of polymorphisms and BIRC5 expression was exposed by in-silico analysis, as well as the effects to tumorigenesis and prognosis. Finally, we enrolled 19 case-control studies to conducted this meta-analysis. An upgrade risk in rs9904341 of BIRC5 were revealed to be associated with urinary cancer in allele contrast model (OR = 1.222, P = 0.012), homozygote contrast model (OR = 1.579, P = 0.0001) and recessive contrast model (OR = 1.433, P < 0.001), as well as rs2071214 polymorphism in the subgroup analysis of BCa in allele contrast model (OR = 1.362, P = 0.011) and recessive contrast model (OR = 1.417, P = 0.015). On the other hand, rs17878467 variant plays an important role in prevent the tumorigenicity of urinary cancer in allele contrast model (OR = 0.672, P = 0.009), heterozygote contrast model (OR = 0.585, P = 0.006) and dominant contrast model (OR = 0.595, P = 0.004). In conclusion, we found that BIRC5 rs9904341, rs2071214 polymorphisms might cause the increased risk of urinary cancer, while rs17878467 reduces risk." @default.
• W2994390015 created "2019-12-13" @default.
• W2994390015 creator A5012258252 @default.
• W2994390015 creator A5074140059 @default.
• W2994390015 creator A5074370959 @default.
• W2994390015 creator A5078288409 @default.
• W2994390015 date "2020-04-01" @default.
• W2994390015 modified "2023-09-23" @default.
• W2994390015 title "What is the impact of BIRC5 gene polymorphisms on urinary cancer susceptibility? Evidence from 9348 subjects" @default.
• W2994390015 cites W1538643690 @default.
• W2994390015 cites W1964435302 @default.
• W2994390015 cites W1975185722 @default.
• W2994390015 cites W1978758051 @default.
• W2994390015 cites W1979886704 @default.
• W2994390015 cites W1982145774 @default.
• W2994390015 cites W1982228885 @default.
• W2994390015 cites W1984156818 @default.
• W2994390015 cites W1986879540 @default.
• W2994390015 cites W2000116033 @default.
• W2994390015 cites W2002125670 @default.
• W2994390015 cites W2022741235 @default.
• W2994390015 cites W2038330194 @default.
• W2994390015 cites W2046521127 @default.
• W2994390015 cites W2053550021 @default.
• W2994390015 cites W2058115449 @default.
• W2994390015 cites W2067605857 @default.
• W2994390015 cites W2078374613 @default.
• W2994390015 cites W2096173332 @default.
• W2994390015 cites W2105102343 @default.
• W2994390015 cites W2107328434 @default.
• W2994390015 cites W2108177262 @default.
• W2994390015 cites W2126930838 @default.
• W2994390015 cites W2133042546 @default.
• W2994390015 cites W2272984102 @default.
• W2994390015 cites W2314951998 @default.
• W2994390015 cites W2318285927 @default.
• W2994390015 cites W2466146321 @default.
• W2994390015 cites W2517215399 @default.
• W2994390015 cites W2589780548 @default.
• W2994390015 cites W2733488454 @default.
• W2994390015 cites W2736730167 @default.
• W2994390015 cites W2744156886 @default.
• W2994390015 cites W2763421636 @default.
• W2994390015 cites W2776712771 @default.
• W2994390015 cites W2781525129 @default.
• W2994390015 cites W2789525724 @default.
• W2994390015 cites W2803774634 @default.
• W2994390015 cites W2890673472 @default.
• W2994390015 cites W2986996296 @default.
• W2994390015 cites W2991792334 @default.
• W2994390015 doi "https://doi.org/10.1016/j.gene.2019.144268" @default.
• W2994390015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31809840" @default.
• W2994390015 hasPublicationYear "2020" @default.
• W2994390015 type Work @default.
• W2994390015 sameAs 2994390015 @default.
• W2994390015 citedByCount "2" @default.
• W2994390015 countsByYear W29943900152021 @default.
• W2994390015 crossrefType "journal-article" @default.
• W2994390015 hasAuthorship W2994390015A5012258252 @default.
• W2994390015 hasAuthorship W2994390015A5074140059 @default.
• W2994390015 hasAuthorship W2994390015A5074370959 @default.
• W2994390015 hasAuthorship W2994390015A5078288409 @default.
• W2994390015 hasConcept C104317684 @default.
• W2994390015 hasConcept C121608353 @default.
• W2994390015 hasConcept C126322002 @default.
• W2994390015 hasConcept C143998085 @default.
• W2994390015 hasConcept C156957248 @default.
• W2994390015 hasConcept C180754005 @default.
• W2994390015 hasConcept C2780439572 @default.
• W2994390015 hasConcept C44249647 @default.
• W2994390015 hasConcept C502942594 @default.
• W2994390015 hasConcept C54355233 @default.
• W2994390015 hasConcept C555283112 @default.
• W2994390015 hasConcept C60644358 @default.
• W2994390015 hasConcept C71924100 @default.
• W2994390015 hasConcept C82605166 @default.
• W2994390015 hasConcept C86803240 @default.
• W2994390015 hasConcept C95190672 @default.
• W2994390015 hasConceptScore W2994390015C104317684 @default.
• W2994390015 hasConceptScore W2994390015C121608353 @default.
• W2994390015 hasConceptScore W2994390015C126322002 @default.
• W2994390015 hasConceptScore W2994390015C143998085 @default.
• W2994390015 hasConceptScore W2994390015C156957248 @default.
• W2994390015 hasConceptScore W2994390015C180754005 @default.
• W2994390015 hasConceptScore W2994390015C2780439572 @default.
• W2994390015 hasConceptScore W2994390015C44249647 @default.
• W2994390015 hasConceptScore W2994390015C502942594 @default.
• W2994390015 hasConceptScore W2994390015C54355233 @default.
• W2994390015 hasConceptScore W2994390015C555283112 @default.
• W2994390015 hasConceptScore W2994390015C60644358 @default.
• W2994390015 hasConceptScore W2994390015C71924100 @default.
• W2994390015 hasConceptScore W2994390015C82605166 @default.
• W2994390015 hasConceptScore W2994390015C86803240 @default.
• W2994390015 hasConceptScore W2994390015C95190672 @default.
• W2994390015 hasFunder F4320321001 @default.
• W2994390015 hasFunder F4320321921 @default.
• W2994390015 hasLocation W29943900151 @default.
• W2994390015 hasLocation W29943900152 @default.
• W2994390015 hasOpenAccess W2994390015 @default.
• W2994390015 hasPrimaryLocation W29943900151 @default.

• next