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• W2994607594 endingPage "127558" @default.
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• W2994607594 abstract "In this work, an electrochemical aptasensor including CoSe2/AuNRs, 3D structured (3 ds) [email protected] networks and nicking enzyme was employed to detect zearalenone (ZEN). Herein, CoSe2/AuNRs with large surface area and high conductivity was synthesized to provide a favorable platform for the construction of aptasensor. 3 ds [email protected] networks with intrinsic catalysis towards thionine (Thi) could largely increase the amount of signal tags Thi and signal amplifiers [email protected] to amplify the current response. When ZEN existed, the aptamer (Apt) was opened to obtain the target complex (ZEN-Apt), thereby further opening hairpin H1 through DNA hybridization. With the aid of nicking enzyme, the ZEN-Apt was released to initiate the next hybridization process, resulting in the production of amounts of residual DNA H1. Thi labeled DNA [email protected] can be introduced by hybridization of residual DNA H1 and hairpin base sequence of DNA H2 to obtain a significantly amplified current. Eventually, higher current was obtained through the further adding of Thi labeled 3 ds [email protected] networks. As a result, the aptasensor exhibited a low detection limit of 1.37 fg/mL (S/N = 3). Furthermore, the resultant aptasensor exhibited satisfactory stability and specificity, and was applied to detect ZEN in maize samples." @default.
• W2994607594 created "2019-12-13" @default.
• W2994607594 creator A5041584117 @default.
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• W2994607594 date "2020-03-01" @default.
• W2994607594 modified "2023-10-16" @default.
• W2994607594 title "Ultrasensitive electrochemical aptasensor based on CoSe2/AuNRs and 3D structured DNA-PtNi@Co-MOF networks for the detection of zearalenone" @default.
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• W2994607594 doi "https://doi.org/10.1016/j.snb.2019.127558" @default.
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