FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2994647402> ?p ?o ?g. }

• W2994647402 abstract "C. perfringens type F strains are a common cause of food poisoning and antibiotic-associated diarrhea. Type F strain virulence requires production of C. perfringens enterotoxin (CPE). In Caco-2 cells, high CPE concentrations cause necrosis while low enterotoxin concentrations induce apoptosis. The current study determined that receptor-interacting serine/threonine-protein kinases 1 and 3 are involved in both CPE-induced apoptosis and necrosis in Caco-2 cells, while mixed-lineage kinase domain-like pseudokinase (MLKL) oligomerization is involved in CPE-induced necrosis, thereby indicating that this form of CPE-induced cell death involves necroptosis. High CPE concentrations also caused necroptosis in T84 and Vero cells. Calpain activation was identified as a key intermediate for CPE-induced necroptosis. These results suggest inhibitors of RIP1, RIP3, MLKL oligomerization, or calpain are useful therapeutics against CPE-mediated diseases." @default.
• W2994647402 created "2019-12-26" @default.
• W2994647402 creator A5048550248 @default.
• W2994647402 creator A5088099999 @default.
• W2994647402 creator A5089450547 @default.
• W2994647402 date "2019-12-24" @default.
• W2994647402 modified "2023-09-25" @default.
• W2994647402 title "RIP1, RIP3, and MLKL Contribute to Cell Death Caused by Clostridium perfringens Enterotoxin" @default.
• W2994647402 cites W113430669 @default.
• W2994647402 cites W1535825866 @default.
• W2994647402 cites W1853713578 @default.
• W2994647402 cites W1866525818 @default.
• W2994647402 cites W1889401367 @default.
• W2994647402 cites W1912374365 @default.
• W2994647402 cites W1965670351 @default.
• W2994647402 cites W1985079080 @default.
• W2994647402 cites W2003786318 @default.
• W2994647402 cites W2018204131 @default.
• W2994647402 cites W2027371168 @default.
• W2994647402 cites W2028833608 @default.
• W2994647402 cites W2063120914 @default.
• W2994647402 cites W2067496406 @default.
• W2994647402 cites W2072086224 @default.
• W2994647402 cites W2081643971 @default.
• W2994647402 cites W2087232320 @default.
• W2994647402 cites W2091363184 @default.
• W2994647402 cites W2097253928 @default.
• W2994647402 cites W2105267058 @default.
• W2994647402 cites W2107204729 @default.
• W2994647402 cites W2128296686 @default.
• W2994647402 cites W2128591134 @default.
• W2994647402 cites W2131148718 @default.
• W2994647402 cites W2131357993 @default.
• W2994647402 cites W2140585013 @default.
• W2994647402 cites W2147891834 @default.
• W2994647402 cites W2149753744 @default.
• W2994647402 cites W2169820248 @default.
• W2994647402 cites W2213915303 @default.
• W2994647402 cites W2220848304 @default.
• W2994647402 cites W2286248913 @default.
• W2994647402 cites W2329801438 @default.
• W2994647402 cites W2336348303 @default.
• W2994647402 cites W2411565536 @default.
• W2994647402 cites W2429745182 @default.
• W2994647402 cites W2514162430 @default.
• W2994647402 cites W2523136825 @default.
• W2994647402 cites W2560438292 @default.
• W2994647402 cites W2562416884 @default.
• W2994647402 cites W2581350551 @default.
• W2994647402 cites W2605086908 @default.
• W2994647402 cites W2749909301 @default.
• W2994647402 cites W2756886812 @default.
• W2994647402 cites W2795155279 @default.
• W2994647402 cites W2796028181 @default.
• W2994647402 cites W2800937934 @default.
• W2994647402 cites W2801410986 @default.
• W2994647402 cites W2805677815 @default.
• W2994647402 cites W2809939144 @default.
• W2994647402 cites W2888018312 @default.
• W2994647402 cites W2935369648 @default.
• W2994647402 cites W4231084292 @default.
• W2994647402 cites W4302867465 @default.
• W2994647402 cites W973230838 @default.
• W2994647402 doi "https://doi.org/10.1128/mbio.02985-19" @default.
• W2994647402 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6918092" @default.
• W2994647402 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31848291" @default.
• W2994647402 hasPublicationYear "2019" @default.
• W2994647402 type Work @default.
• W2994647402 sameAs 2994647402 @default.
• W2994647402 citedByCount "19" @default.
• W2994647402 countsByYear W29946474022019 @default.
• W2994647402 countsByYear W29946474022020 @default.
• W2994647402 countsByYear W29946474022021 @default.
• W2994647402 countsByYear W29946474022022 @default.
• W2994647402 countsByYear W29946474022023 @default.
• W2994647402 crossrefType "journal-article" @default.
• W2994647402 hasAuthorship W2994647402A5048550248 @default.
• W2994647402 hasAuthorship W2994647402A5088099999 @default.
• W2994647402 hasAuthorship W2994647402A5089450547 @default.
• W2994647402 hasBestOaLocation W29946474021 @default.
• W2994647402 hasConcept C104317684 @default.
• W2994647402 hasConcept C184235292 @default.
• W2994647402 hasConcept C185592680 @default.
• W2994647402 hasConcept C190283241 @default.
• W2994647402 hasConcept C2779116991 @default.
• W2994647402 hasConcept C31573885 @default.
• W2994647402 hasConcept C503630168 @default.
• W2994647402 hasConcept C523546767 @default.
• W2994647402 hasConcept C54355233 @default.
• W2994647402 hasConcept C547475151 @default.
• W2994647402 hasConcept C55493867 @default.
• W2994647402 hasConcept C60987743 @default.
• W2994647402 hasConcept C66999527 @default.
• W2994647402 hasConcept C86803240 @default.
• W2994647402 hasConcept C89423630 @default.
• W2994647402 hasConcept C94030615 @default.
• W2994647402 hasConcept C95444343 @default.
• W2994647402 hasConceptScore W2994647402C104317684 @default.
• W2994647402 hasConceptScore W2994647402C184235292 @default.
• W2994647402 hasConceptScore W2994647402C185592680 @default.

• next