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- W2994656481 abstract "Several treatments for cancer, notably cell and gene therapies, are in development, some of which may be curative. The prices of these therapies are expected to be high, and this raises a question among payers about the amount of resources that society would like to allocate to these treatments. Here we report on the attribute development for inclusion in a DCE determining drivers of WTP for curative cancer treatments, in the French general population. A literature search was carried out in Medline and Embase to identify studies reporting characteristics of cancers or other conditions that drive preferences for treatments. Characteristics considered in included studies were extracted and used to prepare a semi-directive interview guide. Members of the French general population were recruited and telephone interviews conducted. Respondents were asked about evaluating cancer severity, awareness of treatments available and reimbursement of treatments. They also completed a ranking exercise on characteristics to be considered when selecting which cancer treatments with 100% efficacy to make available in France. 34 full texts were included. Characteristics reported were related to treatment (n=32 studies), disease (n=18 studies) or population (n=15 studies). 10 respondents completed telephone interviews, with a mean age of 51.7 years (range 19-80) and 50% female. The most frequent characteristics ranked by respondents were related to treatment (n=52 mentions), notably cost (n=10), side effects (n=7), treatment frequency/duration (n=7), and quality of life linked to treatment (n=5). Respondents also ranked disease-related characteristics (n=12 mentions) including symptom severity (n=4) and life expectancy without treatment (n=3), and population-related characteristics (n=12) such as age (n=6) and concomitant diseases (n=4). Six attributes were selected for the DCE: cancer prevalence, patients’ age at diagnosis, pain/discomfort linked to current treatments, patients’ other health issues, survival with current treatments and cost (expressed as increase in social security charges)." @default.
- W2994656481 created "2019-12-26" @default.
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- W2994656481 date "2019-11-01" @default.
- W2994656481 modified "2023-09-30" @default.
- W2994656481 title "PCN297 ATTRIBUTE DEVELOPMENT FOR A DISCRETE CHOICE EXPERIMENT (DCE) EXPLORING WILLINGNESS TO PAY (WTP) FOR CURING CANCER" @default.
- W2994656481 doi "https://doi.org/10.1016/j.jval.2019.09.492" @default.
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