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• W2994694872 abstract "Research indicates that insomnia improvement plays a critical role in depression symptom improvement. In line with the National Institute of Mental Health Experimental Therapeutics approach recent research focuses on identifying specific mechanisms; the present manuscript aims to review recent research on one potential mechanism, dysfunction in the HPA axis which is a shared biological substrate of both depression and insomnia. Over the past five years, research demonstrated a relationship between sleep disturbance and cortisol reactivity and recovery following a stressor. Meanwhile, research on the relationship between depression and HPA axis functioning is less consistent and is dependent on measurement of HPA axis. Experimental research that aims to determine a causal pathway between sleep, depression and HPA axis functioning is needed." @default.
• W2994694872 created "2019-12-26" @default.
• W2994694872 creator A5032945062 @default.
• W2994694872 date "2020-08-01" @default.
• W2994694872 modified "2023-10-02" @default.
• W2994694872 title "Depression and sleep: what has the treatment research revealed and could the HPA axis be a potential mechanism?" @default.
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• W2994694872 doi "https://doi.org/10.1016/j.copsyc.2019.12.002" @default.
• W2994694872 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8412030" @default.
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