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• W2995008358 abstract "A large body of literature has established an association of social relationship characteristics with premature mortality and recent evidence suggests that systemic inflammation may mediate this association. However, the literature examining the link between social relationships and inflammation using healthy samples is limited by 1) the use of cross-sectional designs, 2) few methodologically rigorous longitudinal studies, 3) cursory measures of social relationships, and 4) failure to explore mechanisms accounting for any significant effects. To address these limitations, the current study used growth curve modeling to test the prospective association of perceived support, social integration, and marital satisfaction with the rate of change of inflammatory biomarkers, CRP and IL-6 in healthy, older adults. In the case of any significant effects, the study planned to test interpersonal (i.e. social interactions), affective (i.e. positive/negative affect), and behavioral (i.e. obesity, smoking, sleep duration) variables as mechanisms of overall effects using mediation analyses. Questionnaire measures of social integration, perceived social support, and marital satisfaction were collected at baseline, inflammatory biomarkers and health behaviors (with the exception of sleep duration) were measured at all 3 time-points, and social interaction characteristics and affect were measured using ecological momentary assessment (EMA) at baseline and 6-year follow up. Results showed no significant prospective association of social integration, perceived support, or marital quality with the rate of change in IL-6 and CRP over a 6-year period. Additionally, perceived social support did not buffer the deleterious effect of chronic stress on the longitudinal changes in these biomarkers. Given lack of direct effects, longitudinal mediation analyses were not pursued. Exploratory analyses testing social interactions as independent predictors of the longitudinal changes in IL-6 and CRP showed that higher frequency of negative interactions with a spouse in daily life was associated with higher initial levels of IL-6, adding to the body of work examining the link between marital quality and inflammation. The non-significant prospective associations in the main analyses may, in large part, be due to the lack of power in the current study, as well as due to homogeneity in social behavior and health characteristics in this sample." @default.
• W2995008358 created "2019-12-26" @default.
• W2995008358 creator A5037967265 @default.
• W2995008358 date "2019-09-24" @default.
• W2995008358 modified "2023-09-27" @default.
• W2995008358 title "The Longitudinal Association of Social Relationship Characteristics With Circulating Markers of Inflammation and Potential Mechanisms in Healthy Older Adults" @default.
• W2995008358 cites W1495444321 @default.
• W2995008358 cites W1565069986 @default.
• W2995008358 cites W167636076 @default.
• W2995008358 cites W1964099936 @default.
• W2995008358 cites W1964607854 @default.
• W2995008358 cites W1964744961 @default.
• W2995008358 cites W1968169988 @default.
• W2995008358 cites W1972840292 @default.
• W2995008358 cites W1973139201 @default.
• W2995008358 cites W1976999651 @default.
• W2995008358 cites W1977376053 @default.
• W2995008358 cites W1977570615 @default.
• W2995008358 cites W1979615936 @default.
• W2995008358 cites W1979912452 @default.
• W2995008358 cites W1982683121 @default.
• W2995008358 cites W1984460050 @default.
• W2995008358 cites W1992126288 @default.
• W2995008358 cites W1993722036 @default.
• W2995008358 cites W1994219219 @default.
• W2995008358 cites W1994330837 @default.
• W2995008358 cites W1994913549 @default.
• W2995008358 cites W1995525413 @default.
• W2995008358 cites W2000395451 @default.
• W2995008358 cites W2001652786 @default.
• W2995008358 cites W2003490123 @default.
• W2995008358 cites W2004446197 @default.
• W2995008358 cites W2005070648 @default.
• W2995008358 cites W2005078721 @default.
• W2995008358 cites W2008384192 @default.
• W2995008358 cites W2010027177 @default.
• W2995008358 cites W2011769870 @default.
• W2995008358 cites W2012376464 @default.
• W2995008358 cites W2021723318 @default.
• W2995008358 cites W2022283554 @default.
• W2995008358 cites W2025963268 @default.
• W2995008358 cites W2028099244 @default.
• W2995008358 cites W2034067099 @default.
• W2995008358 cites W2036586898 @default.
• W2995008358 cites W2043892556 @default.
• W2995008358 cites W2045883408 @default.
• W2995008358 cites W2045903419 @default.
• W2995008358 cites W2046572145 @default.
• W2995008358 cites W2047223731 @default.
• W2995008358 cites W2049150790 @default.
• W2995008358 cites W2055461003 @default.
• W2995008358 cites W2055737465 @default.
• W2995008358 cites W2057069910 @default.
• W2995008358 cites W2057104059 @default.
• W2995008358 cites W2059115526 @default.
• W2995008358 cites W2059241538 @default.
• W2995008358 cites W2059406405 @default.
• W2995008358 cites W2062145099 @default.
• W2995008358 cites W2062478357 @default.
• W2995008358 cites W2064812121 @default.
• W2995008358 cites W2071666535 @default.
• W2995008358 cites W2072400024 @default.
• W2995008358 cites W2073529494 @default.
• W2995008358 cites W2077395158 @default.
• W2995008358 cites W2079092391 @default.
• W2995008358 cites W2079730234 @default.
• W2995008358 cites W2086951593 @default.
• W2995008358 cites W2090086221 @default.
• W2995008358 cites W2090118127 @default.
• W2995008358 cites W2094022841 @default.
• W2995008358 cites W2094845811 @default.
• W2995008358 cites W2094941678 @default.
• W2995008358 cites W2094965525 @default.
• W2995008358 cites W2095102834 @default.
• W2995008358 cites W2096971946 @default.
• W2995008358 cites W2097555745 @default.
• W2995008358 cites W2097909227 @default.
• W2995008358 cites W2107309535 @default.
• W2995008358 cites W2109216246 @default.
• W2995008358 cites W2111843564 @default.
• W2995008358 cites W2113112139 @default.
• W2995008358 cites W2115552364 @default.
• W2995008358 cites W2117119036 @default.
• W2995008358 cites W2117252492 @default.
• W2995008358 cites W2118561825 @default.
• W2995008358 cites W2119490985 @default.
• W2995008358 cites W2121074427 @default.
• W2995008358 cites W2122311887 @default.
• W2995008358 cites W2125381870 @default.
• W2995008358 cites W2129025140 @default.
• W2995008358 cites W2130069961 @default.
• W2995008358 cites W2133981480 @default.
• W2995008358 cites W2135276646 @default.
• W2995008358 cites W2135877653 @default.
• W2995008358 cites W2135944282 @default.
• W2995008358 cites W2137795540 @default.
• W2995008358 cites W2138109167 @default.
• W2995008358 cites W2138155652 @default.
• W2995008358 cites W2139186181 @default.
• W2995008358 cites W2139546352 @default.

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