FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2995025557> ?p ?o ?g. }

• W2995025557 abstract "Abstract Background LDL cholesterol (LDL-C) concentration is modified by dietary and genetic factors; however, little is known about the details of this relationship. Our aim was to investigate the associations taking into account dietary assessment methods, seasonal effects and missing values. Methods Study subjects completed food frequency questionnaires (FFQ) and supplied 3-day weighed dietary records (WDRs) and blood samples in four seasons. Approximately 660,000 single nucleotide polymorphisms (SNPs) were measured. Candidate SNPs related to LDL-C concentration were systematically selected. Multiple imputation was applied for missing values. A total of 312 repeated measures data were used for analyses. After adjusting for season and subjects as fixed and random effects, effects of nutrient intake and SNPs on LDL-C concentration were assessed according to three dietary assessment methods: the FFQ and first and four season 3-day WDRs (4 s-3d WDRs). Results For LDL-C concentration, ethanol consumption derived from all three dietary assessment methods was consistently associated ( P < 0.09 for all). Positive and negative relationships were consistently shown with rs651007 and rs1160985 in the first and four seasons; but the latter remained after adjusting for total dietary fiber intake derived from the FFQ and 4 s-3d WDRs ( P < 0.05, excepting the first 3-day WDRs). rs599839 was negatively associated after cholesterol intakes derived from the first and 4 s-3d WDRs were considered ( P < 0.05 and 0.07, respectively). Each rs17145738 and ethanol consumption based on the 4 s-3d WDRs was related to LDL-C concentration ( P < 0.05). Seasonal variations of LDL-C concentration were observed only in summer. Conclusions In contrast to nutrient intake, ethanol consumption was shown to be comprehensively related to LDL-C concentration, regardless of dietary assessment methods. Taking into account seasonal effects, critical relationships with LDL-C concentration for some SNPs, after adjustment for specific nutrients, were revealed. Our findings can be used to help to interpret the relationships between dietary and genetic factors on LDL-C concentration in large-scale epidemiological studies. (10/10 keywords)" @default.
• W2995025557 created "2019-12-26" @default.
• W2995025557 creator A5012452436 @default.
• W2995025557 creator A5030360813 @default.
• W2995025557 creator A5062142622 @default.
• W2995025557 date "2019-12-01" @default.
• W2995025557 modified "2023-10-18" @default.
• W2995025557 title "Relationship between ethanol consumption and TBL2 rs17145738 on LDL-C concentration in Japanese adults: a four season 3-day weighed diet record study" @default.
• W2995025557 cites W146555434 @default.
• W2995025557 cites W1487785114 @default.
• W2995025557 cites W1795144871 @default.
• W2995025557 cites W1918132278 @default.
• W2995025557 cites W1978496908 @default.
• W2995025557 cites W1978853058 @default.
• W2995025557 cites W1994059203 @default.
• W2995025557 cites W2004306167 @default.
• W2995025557 cites W2011199151 @default.
• W2995025557 cites W2011720676 @default.
• W2995025557 cites W2017602185 @default.
• W2995025557 cites W2021708309 @default.
• W2995025557 cites W2036691589 @default.
• W2995025557 cites W2049728098 @default.
• W2995025557 cites W2051906439 @default.
• W2995025557 cites W2058073761 @default.
• W2995025557 cites W2065974896 @default.
• W2995025557 cites W2071152788 @default.
• W2995025557 cites W2088144916 @default.
• W2995025557 cites W2090392937 @default.
• W2995025557 cites W2094311270 @default.
• W2995025557 cites W2095703660 @default.
• W2995025557 cites W2104177528 @default.
• W2995025557 cites W2111099202 @default.
• W2995025557 cites W2115098571 @default.
• W2995025557 cites W2116404316 @default.
• W2995025557 cites W2118911665 @default.
• W2995025557 cites W2129328887 @default.
• W2995025557 cites W2135185355 @default.
• W2995025557 cites W2140020569 @default.
• W2995025557 cites W2140079333 @default.
• W2995025557 cites W2163059250 @default.
• W2995025557 cites W2163084301 @default.
• W2995025557 cites W2174245956 @default.
• W2995025557 cites W2509676484 @default.
• W2995025557 cites W2528524934 @default.
• W2995025557 cites W2586619797 @default.
• W2995025557 cites W2600693125 @default.
• W2995025557 cites W2604389865 @default.
• W2995025557 cites W2766108576 @default.
• W2995025557 cites W2789833091 @default.
• W2995025557 cites W627674027 @default.
• W2995025557 cites W65377277 @default.
• W2995025557 doi "https://doi.org/10.1186/s40795-019-0315-6" @default.
• W2995025557 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7050859" @default.
• W2995025557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32153974" @default.
• W2995025557 hasPublicationYear "2019" @default.
• W2995025557 type Work @default.
• W2995025557 sameAs 2995025557 @default.
• W2995025557 citedByCount "1" @default.
• W2995025557 countsByYear W29950255572023 @default.
• W2995025557 crossrefType "journal-article" @default.
• W2995025557 hasAuthorship W2995025557A5012452436 @default.
• W2995025557 hasAuthorship W2995025557A5030360813 @default.
• W2995025557 hasAuthorship W2995025557A5062142622 @default.
• W2995025557 hasBestOaLocation W29950255571 @default.
• W2995025557 hasConcept C104317684 @default.
• W2995025557 hasConcept C105795698 @default.
• W2995025557 hasConcept C126322002 @default.
• W2995025557 hasConcept C135763542 @default.
• W2995025557 hasConcept C140793950 @default.
• W2995025557 hasConcept C148257392 @default.
• W2995025557 hasConcept C153209595 @default.
• W2995025557 hasConcept C2778163477 @default.
• W2995025557 hasConcept C2780662849 @default.
• W2995025557 hasConcept C3019550498 @default.
• W2995025557 hasConcept C33923547 @default.
• W2995025557 hasConcept C55493867 @default.
• W2995025557 hasConcept C58041806 @default.
• W2995025557 hasConcept C71924100 @default.
• W2995025557 hasConcept C86803240 @default.
• W2995025557 hasConcept C9357733 @default.
• W2995025557 hasConceptScore W2995025557C104317684 @default.
• W2995025557 hasConceptScore W2995025557C105795698 @default.
• W2995025557 hasConceptScore W2995025557C126322002 @default.
• W2995025557 hasConceptScore W2995025557C135763542 @default.
• W2995025557 hasConceptScore W2995025557C140793950 @default.
• W2995025557 hasConceptScore W2995025557C148257392 @default.
• W2995025557 hasConceptScore W2995025557C153209595 @default.
• W2995025557 hasConceptScore W2995025557C2778163477 @default.
• W2995025557 hasConceptScore W2995025557C2780662849 @default.
• W2995025557 hasConceptScore W2995025557C3019550498 @default.
• W2995025557 hasConceptScore W2995025557C33923547 @default.
• W2995025557 hasConceptScore W2995025557C55493867 @default.
• W2995025557 hasConceptScore W2995025557C58041806 @default.
• W2995025557 hasConceptScore W2995025557C71924100 @default.
• W2995025557 hasConceptScore W2995025557C86803240 @default.
• W2995025557 hasConceptScore W2995025557C9357733 @default.
• W2995025557 hasIssue "1" @default.
• W2995025557 hasLocation W29950255571 @default.
• W2995025557 hasLocation W29950255572 @default.
• W2995025557 hasLocation W29950255573 @default.

• next