Matches in SemOpenAlex for { <https://semopenalex.org/work/W2995439458> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2995439458 endingPage "e296" @default.
- W2995439458 startingPage "e296" @default.
- W2995439458 abstract "Introduction - The aim of our study was to identify preoperative and intraoperative factors associated with in-hospital mortality after repair of intact abdominal aortic or iliac aneurysms. Methods - This was a retrospective analysis of prospectively collected information on patients undergoing repair of intact aortoiliac aneurysms during a 28-year period. Recorded information included preoperative demographics, risk factors and co-morbidities, aneurysm characteristics, investigations and operative variables including special aneurysm presentation (inflammatory, mycotic/infected, aortocaval fistula) and procedure type (open vs. endovascular repair). Univariate and multivariate logistic regression analyses (with odds ratios, OR) were performed, the latter performed to develop a predictive model using the generated output. The area under the curve of the receiver operating characteristics (ROC) curve of our score, the Glasgow aneurysm score (GAS),1 and the Vascular Study Group of New England (VSGNE) score,2 was calculated. Results - During the study period we operated on 931 patients with intact aortoiliac aneurysms, on an elective (n=882) or urgent (n=49) basis, and an in-hospital mortality of 1.7% and 8.2%, respectively (p=0.015). Endovascular aneurysm repair (EVAR, n=414) was a predictor of lower mortality (0.5% vs. 3.3% for open repair, n=517, p=0.003). Other significant predictors included the presence of abdominal or back pain (7.5% vs 1.3% for no pain, p<0.001), preoperative angiography (6.9% vs 1.6% for no angiography, p=0.01), special aneurysm presentation (10.7% vs 1.5% for 875 ordinary atherosclerotic aneurysms, p<0.001), concomitant major procedures (19% vs 1.6% for the rest, p<0.001), serious intraoperative complications (9.1% vs 1.5% for no such complications, p<0.001), median number of transfused units of blood intraoperatively (2 and 0 for cases with and without mortality, respectively, p<0.001) and duration of the procedure (300min and 150min for cases with and without mortality, respectively, p<0.001). On multivariate analysis, EVAR was an independent predictor of lower mortality (OR=0.22, p=0.05) and special aneurysm presentation (OR=6.45, p=0.001) and concomitant major procedures (OR=14.3, p<0.001) were independent predictors of higher mortality. The area under the ROC curve, and p values for the GAS, VSGNE score and our score was 0.46, 0.62 and 0.81, and 0.59, 0.084 and 0.00003, respectively (Figure). The difference between the VSGNE and our score was significant (p=0.029). Repeat analysis for electively operated cases demonstrated an area under the ROC curve of 0.66 (p=0.029) and 0.80 (p=0.000069), respectively, for the VSGNE and our score, with the difference becoming non-significant. Conclusion - Our study in patients undergoing aortoiliac aneurysm repair has demonstrated novel risk factors for mortality and externally validated VSGNE in different healthcare settings. References1.Samy AK, Murray G, MacBain G. Glasgow aneurysm score. Cardiovasc Surg. 1994;2:41-4.2.Eslami MH, Rybin D, Doros G, Kalish JA, Farber A. Comparison of a Vascular Study Group of New England risk prediction model with established risk prediction models of in-hospital mortality after elective abdominal aortic aneurysm repair. J Vasc Surg. 2015;62:1125-33." @default.
- W2995439458 created "2019-12-26" @default.
- W2995439458 creator A5006486771 @default.
- W2995439458 creator A5010382814 @default.
- W2995439458 creator A5035457862 @default.
- W2995439458 creator A5043811919 @default.
- W2995439458 creator A5046001613 @default.
- W2995439458 creator A5061983627 @default.
- W2995439458 creator A5068331686 @default.
- W2995439458 creator A5075852277 @default.
- W2995439458 date "2019-12-01" @default.
- W2995439458 modified "2023-09-30" @default.
- W2995439458 title "Novel Predictors of Peri-Operative Mortality in a Series Of 931 Consecutive Patients with Intact Aortoiliac Aneurysms Managed at a Single Centre" @default.
- W2995439458 doi "https://doi.org/10.1016/j.ejvs.2019.06.903" @default.
- W2995439458 hasPublicationYear "2019" @default.
- W2995439458 type Work @default.
- W2995439458 sameAs 2995439458 @default.
- W2995439458 citedByCount "0" @default.
- W2995439458 crossrefType "journal-article" @default.
- W2995439458 hasAuthorship W2995439458A5006486771 @default.
- W2995439458 hasAuthorship W2995439458A5010382814 @default.
- W2995439458 hasAuthorship W2995439458A5035457862 @default.
- W2995439458 hasAuthorship W2995439458A5043811919 @default.
- W2995439458 hasAuthorship W2995439458A5046001613 @default.
- W2995439458 hasAuthorship W2995439458A5061983627 @default.
- W2995439458 hasAuthorship W2995439458A5068331686 @default.
- W2995439458 hasAuthorship W2995439458A5075852277 @default.
- W2995439458 hasBestOaLocation W29954394581 @default.
- W2995439458 hasConcept C126322002 @default.
- W2995439458 hasConcept C126838900 @default.
- W2995439458 hasConcept C141071460 @default.
- W2995439458 hasConcept C144301174 @default.
- W2995439458 hasConcept C151956035 @default.
- W2995439458 hasConcept C156957248 @default.
- W2995439458 hasConcept C167135981 @default.
- W2995439458 hasConcept C2776098176 @default.
- W2995439458 hasConcept C2776543907 @default.
- W2995439458 hasConcept C2777010666 @default.
- W2995439458 hasConcept C2777323849 @default.
- W2995439458 hasConcept C2778789114 @default.
- W2995439458 hasConcept C2779384505 @default.
- W2995439458 hasConcept C2779993416 @default.
- W2995439458 hasConcept C2780120127 @default.
- W2995439458 hasConcept C2780643987 @default.
- W2995439458 hasConcept C2781347138 @default.
- W2995439458 hasConcept C38180746 @default.
- W2995439458 hasConcept C58471807 @default.
- W2995439458 hasConcept C71924100 @default.
- W2995439458 hasConceptScore W2995439458C126322002 @default.
- W2995439458 hasConceptScore W2995439458C126838900 @default.
- W2995439458 hasConceptScore W2995439458C141071460 @default.
- W2995439458 hasConceptScore W2995439458C144301174 @default.
- W2995439458 hasConceptScore W2995439458C151956035 @default.
- W2995439458 hasConceptScore W2995439458C156957248 @default.
- W2995439458 hasConceptScore W2995439458C167135981 @default.
- W2995439458 hasConceptScore W2995439458C2776098176 @default.
- W2995439458 hasConceptScore W2995439458C2776543907 @default.
- W2995439458 hasConceptScore W2995439458C2777010666 @default.
- W2995439458 hasConceptScore W2995439458C2777323849 @default.
- W2995439458 hasConceptScore W2995439458C2778789114 @default.
- W2995439458 hasConceptScore W2995439458C2779384505 @default.
- W2995439458 hasConceptScore W2995439458C2779993416 @default.
- W2995439458 hasConceptScore W2995439458C2780120127 @default.
- W2995439458 hasConceptScore W2995439458C2780643987 @default.
- W2995439458 hasConceptScore W2995439458C2781347138 @default.
- W2995439458 hasConceptScore W2995439458C38180746 @default.
- W2995439458 hasConceptScore W2995439458C58471807 @default.
- W2995439458 hasConceptScore W2995439458C71924100 @default.
- W2995439458 hasIssue "6" @default.
- W2995439458 hasLocation W29954394581 @default.
- W2995439458 hasOpenAccess W2995439458 @default.
- W2995439458 hasPrimaryLocation W29954394581 @default.
- W2995439458 hasRelatedWork W157654193 @default.
- W2995439458 hasRelatedWork W1730039455 @default.
- W2995439458 hasRelatedWork W1963977372 @default.
- W2995439458 hasRelatedWork W2027675095 @default.
- W2995439458 hasRelatedWork W2056923344 @default.
- W2995439458 hasRelatedWork W2077292425 @default.
- W2995439458 hasRelatedWork W2107952077 @default.
- W2995439458 hasRelatedWork W2118424145 @default.
- W2995439458 hasRelatedWork W3163115693 @default.
- W2995439458 hasRelatedWork W2507266917 @default.
- W2995439458 hasVolume "58" @default.
- W2995439458 isParatext "false" @default.
- W2995439458 isRetracted "false" @default.
- W2995439458 magId "2995439458" @default.
- W2995439458 workType "article" @default.