FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2995453701> ?p ?o ?g. }

• W2995453701 endingPage "269" @default.
• W2995453701 startingPage "260" @default.
• W2995453701 abstract "ObjectiveTo study the impact of increased dietary intake of omega-3 fatty acids, vitamin D, and olive oil for 6 weeks before in vitro fertilization (IVF) or IVF–intracytoplasmic sperm injection (ICSI) on morphokinetic markers of early embryo development.DesignA double-blinded randomized controlled trial.SettingAcademic IVF unit.Patient(s)A total of 111 couples undergoing IVF or IVF-ICSI were recruited.Interventions(s)Fifty-five couples received the 6-week study intervention of a daily supplement drink enriched with omega-3 fatty acids and vitamin D plus additional olive oil and olive oil–based spread, and 56 couples received the control intervention.Main Outcome Measure(s)The primary end point for the study was the time taken for completion of the second cell cycle after fertilization (CC2). Secondary end points included time to complete the third and fourth cell cycles (CC3 and CC4), the synchrony of the second and third cell cycles (S2 and S3), and the day 3 and day 5 Known Implantation Data Scores (KIDScores).Result(s)There was no difference in CC2 between the two groups. However, CC4 was accelerated in the study group compared with the control group, and a significantly shortened S3 as well as an increase in KIDScore on day 3 were observed, indicating improved embryo quality in the study group.Conclusion(s)This study demonstrates that a short period of dietary supplementation alters the rate of embryo cleavage. Further research is required to investigate the mechanisms that regulate this effect, and whether the impact on embryo development translates into improved clinical outcomes.Clinical Trial Registration NumberISRCTN50956936 To study the impact of increased dietary intake of omega-3 fatty acids, vitamin D, and olive oil for 6 weeks before in vitro fertilization (IVF) or IVF–intracytoplasmic sperm injection (ICSI) on morphokinetic markers of early embryo development. A double-blinded randomized controlled trial. Academic IVF unit. A total of 111 couples undergoing IVF or IVF-ICSI were recruited. Fifty-five couples received the 6-week study intervention of a daily supplement drink enriched with omega-3 fatty acids and vitamin D plus additional olive oil and olive oil–based spread, and 56 couples received the control intervention. The primary end point for the study was the time taken for completion of the second cell cycle after fertilization (CC2). Secondary end points included time to complete the third and fourth cell cycles (CC3 and CC4), the synchrony of the second and third cell cycles (S2 and S3), and the day 3 and day 5 Known Implantation Data Scores (KIDScores). There was no difference in CC2 between the two groups. However, CC4 was accelerated in the study group compared with the control group, and a significantly shortened S3 as well as an increase in KIDScore on day 3 were observed, indicating improved embryo quality in the study group. This study demonstrates that a short period of dietary supplementation alters the rate of embryo cleavage. Further research is required to investigate the mechanisms that regulate this effect, and whether the impact on embryo development translates into improved clinical outcomes." @default.
• W2995453701 created "2019-12-26" @default.
• W2995453701 creator A5024858156 @default.
• W2995453701 creator A5028618056 @default.
• W2995453701 creator A5035991142 @default.
• W2995453701 creator A5054357651 @default.
• W2995453701 creator A5066362474 @default.
• W2995453701 creator A5072400539 @default.
• W2995453701 creator A5074645101 @default.
• W2995453701 creator A5079813676 @default.
• W2995453701 creator A5085083937 @default.
• W2995453701 creator A5085590104 @default.
• W2995453701 date "2020-02-01" @default.
• W2995453701 modified "2023-10-10" @default.
• W2995453701 title "Effect of a 6-week “Mediterranean” dietary intervention on in vitro human embryo development: the Preconception Dietary Supplements in Assisted Reproduction double-blinded randomized controlled trial" @default.
• W2995453701 cites W1498264251 @default.
• W2995453701 cites W1964465516 @default.
• W2995453701 cites W1968230639 @default.
• W2995453701 cites W1971226672 @default.
• W2995453701 cites W1971688485 @default.
• W2995453701 cites W1972079299 @default.
• W2995453701 cites W1976277318 @default.
• W2995453701 cites W1981493487 @default.
• W2995453701 cites W1987614027 @default.
• W2995453701 cites W1993138318 @default.
• W2995453701 cites W2009434612 @default.
• W2995453701 cites W2017202779 @default.
• W2995453701 cites W2034107956 @default.
• W2995453701 cites W2074754568 @default.
• W2995453701 cites W2080018890 @default.
• W2995453701 cites W2081857095 @default.
• W2995453701 cites W2087182466 @default.
• W2995453701 cites W2093124273 @default.
• W2995453701 cites W2102194053 @default.
• W2995453701 cites W2110475447 @default.
• W2995453701 cites W2124381929 @default.
• W2995453701 cites W2125161176 @default.
• W2995453701 cites W2130462088 @default.
• W2995453701 cites W2137501646 @default.
• W2995453701 cites W2141936301 @default.
• W2995453701 cites W2143659187 @default.
• W2995453701 cites W2146257100 @default.
• W2995453701 cites W2150526592 @default.
• W2995453701 cites W2153114583 @default.
• W2995453701 cites W2161387565 @default.
• W2995453701 cites W2167131018 @default.
• W2995453701 cites W2228991651 @default.
• W2995453701 cites W2252403865 @default.
• W2995453701 cites W2498182268 @default.
• W2995453701 cites W2517067289 @default.
• W2995453701 cites W2566255048 @default.
• W2995453701 cites W2571560994 @default.
• W2995453701 cites W2735378914 @default.
• W2995453701 cites W2747943965 @default.
• W2995453701 cites W2789435639 @default.
• W2995453701 cites W2791486141 @default.
• W2995453701 cites W2803223043 @default.
• W2995453701 cites W2901194289 @default.
• W2995453701 cites W2921138700 @default.
• W2995453701 doi "https://doi.org/10.1016/j.fertnstert.2019.09.041" @default.
• W2995453701 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31870562" @default.
• W2995453701 hasPublicationYear "2020" @default.
• W2995453701 type Work @default.
• W2995453701 sameAs 2995453701 @default.
• W2995453701 citedByCount "33" @default.
• W2995453701 countsByYear W29954537012020 @default.
• W2995453701 countsByYear W29954537012021 @default.
• W2995453701 countsByYear W29954537012022 @default.
• W2995453701 countsByYear W29954537012023 @default.
• W2995453701 crossrefType "journal-article" @default.
• W2995453701 hasAuthorship W2995453701A5024858156 @default.
• W2995453701 hasAuthorship W2995453701A5028618056 @default.
• W2995453701 hasAuthorship W2995453701A5035991142 @default.
• W2995453701 hasAuthorship W2995453701A5054357651 @default.
• W2995453701 hasAuthorship W2995453701A5066362474 @default.
• W2995453701 hasAuthorship W2995453701A5072400539 @default.
• W2995453701 hasAuthorship W2995453701A5074645101 @default.
• W2995453701 hasAuthorship W2995453701A5079813676 @default.
• W2995453701 hasAuthorship W2995453701A5085083937 @default.
• W2995453701 hasAuthorship W2995453701A5085590104 @default.
• W2995453701 hasBestOaLocation W29954537011 @default.
• W2995453701 hasConcept C105702510 @default.
• W2995453701 hasConcept C126322002 @default.
• W2995453701 hasConcept C16685009 @default.
• W2995453701 hasConcept C168563851 @default.
• W2995453701 hasConcept C19038510 @default.
• W2995453701 hasConcept C196843134 @default.
• W2995453701 hasConcept C2777542035 @default.
• W2995453701 hasConcept C2777551382 @default.
• W2995453701 hasConcept C2778004101 @default.
• W2995453701 hasConcept C2778278907 @default.
• W2995453701 hasConcept C2779335785 @default.
• W2995453701 hasConcept C29456083 @default.
• W2995453701 hasConcept C42407357 @default.
• W2995453701 hasConcept C512716672 @default.
• W2995453701 hasConcept C543025807 @default.
• W2995453701 hasConcept C55493867 @default.
• W2995453701 hasConcept C71924100 @default.

• next