FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2995599975> ?p ?o ?g. }

• W2995599975 endingPage "626" @default.
• W2995599975 startingPage "615" @default.
• W2995599975 abstract "Study objectivePalliative patients often visit the emergency department (ED) with respiratory distress during their end-of-life period. The goal of management is alleviating dyspnea and providing comfort. High-flow nasal cannula may be an alternative oxygen-delivering method for palliative patients with do-not-intubate status. We therefore aim to compare the efficacy of high-flow nasal cannula with conventional oxygen therapy in improving dyspnea of palliative patients with do-not-intubate status who have hypoxemic respiratory failure in the ED.MethodsThis randomized, nonblinded, crossover study was conducted with 48 palliative patients aged 18 years or older with do-not-intubate status who presented with hypoxemic respiratory failure to the ED of Siriraj Hospital, Bangkok, Thailand. The participants were randomly allocated to conventional oxygen therapy for 60 minutes, followed by high-flow nasal cannula for 60 minutes (n=24) or vice versa (n=24). The primary outcome was modified Borg scale score. The secondary outcomes were numeric rating scale score of dyspnea and vital signs.ResultsIntention-to-treat analysis included 44 patients, 22 in each group. Baseline mean modified Borg scale score was 7.6 (SD 2.2) (conventional oxygen therapy first) and 8.2 (SD 1.8) (high-flow nasal cannula first). At 60 minutes, mean modified Borg scale score in patients receiving conventional oxygen therapy and high-flow nasal cannula was 4.9 (standard of mean 0.3) and 2.9 (standard of mean 0.3), respectively (mean difference 2.0; 95% confidence interval 1.4 to 2.6). Results for the numeric rating scale score of dyspnea were similar to those for the modified Borg scale score. Respiratory rates were lower with high-flow nasal cannula (mean difference 5.9; 95% confidence interval 3.5 to 8.3), and high-flow nasal cannula was associated with a significantly lower first-hour morphine dose.ConclusionHigh-flow nasal cannula was superior to conventional oxygen therapy in reducing the severity of dyspnea in the first hour of treatment in patients with do-not-intubate status and hypoxemic respiratory failure. Palliative patients often visit the emergency department (ED) with respiratory distress during their end-of-life period. The goal of management is alleviating dyspnea and providing comfort. High-flow nasal cannula may be an alternative oxygen-delivering method for palliative patients with do-not-intubate status. We therefore aim to compare the efficacy of high-flow nasal cannula with conventional oxygen therapy in improving dyspnea of palliative patients with do-not-intubate status who have hypoxemic respiratory failure in the ED. This randomized, nonblinded, crossover study was conducted with 48 palliative patients aged 18 years or older with do-not-intubate status who presented with hypoxemic respiratory failure to the ED of Siriraj Hospital, Bangkok, Thailand. The participants were randomly allocated to conventional oxygen therapy for 60 minutes, followed by high-flow nasal cannula for 60 minutes (n=24) or vice versa (n=24). The primary outcome was modified Borg scale score. The secondary outcomes were numeric rating scale score of dyspnea and vital signs. Intention-to-treat analysis included 44 patients, 22 in each group. Baseline mean modified Borg scale score was 7.6 (SD 2.2) (conventional oxygen therapy first) and 8.2 (SD 1.8) (high-flow nasal cannula first). At 60 minutes, mean modified Borg scale score in patients receiving conventional oxygen therapy and high-flow nasal cannula was 4.9 (standard of mean 0.3) and 2.9 (standard of mean 0.3), respectively (mean difference 2.0; 95% confidence interval 1.4 to 2.6). Results for the numeric rating scale score of dyspnea were similar to those for the modified Borg scale score. Respiratory rates were lower with high-flow nasal cannula (mean difference 5.9; 95% confidence interval 3.5 to 8.3), and high-flow nasal cannula was associated with a significantly lower first-hour morphine dose. High-flow nasal cannula was superior to conventional oxygen therapy in reducing the severity of dyspnea in the first hour of treatment in patients with do-not-intubate status and hypoxemic respiratory failure." @default.
• W2995599975 created "2019-12-26" @default.
• W2995599975 creator A5013441728 @default.
• W2995599975 creator A5014794514 @default.
• W2995599975 creator A5019783998 @default.
• W2995599975 creator A5035042761 @default.
• W2995599975 creator A5039246923 @default.
• W2995599975 creator A5060219276 @default.
• W2995599975 creator A5062313023 @default.
• W2995599975 creator A5081845323 @default.
• W2995599975 creator A5086516359 @default.
• W2995599975 creator A5091673971 @default.
• W2995599975 date "2020-05-01" @default.
• W2995599975 modified "2023-10-18" @default.
• W2995599975 title "High-Flow Nasal Cannula Versus Conventional Oxygen Therapy in Relieving Dyspnea in Emergency Palliative Patients With Do-Not-Intubate Status: A Randomized Crossover Study" @default.
• W2995599975 cites W1910949404 @default.
• W2995599975 cites W1969924153 @default.
• W2995599975 cites W1999901734 @default.
• W2995599975 cites W2004008756 @default.
• W2995599975 cites W2010702762 @default.
• W2995599975 cites W2016399728 @default.
• W2995599975 cites W2020616079 @default.
• W2995599975 cites W2031820762 @default.
• W2995599975 cites W2034876615 @default.
• W2995599975 cites W2044143599 @default.
• W2995599975 cites W2058657391 @default.
• W2995599975 cites W2097590575 @default.
• W2995599975 cites W2111662768 @default.
• W2995599975 cites W2112182062 @default.
• W2995599975 cites W2121908546 @default.
• W2995599975 cites W2124669317 @default.
• W2995599975 cites W2159822959 @default.
• W2995599975 cites W2171503496 @default.
• W2995599975 cites W2199023581 @default.
• W2995599975 cites W2308520264 @default.
• W2995599975 cites W2312207715 @default.
• W2995599975 cites W2341347386 @default.
• W2995599975 cites W2626406916 @default.
• W2995599975 cites W2794904755 @default.
• W2995599975 cites W2811174811 @default.
• W2995599975 doi "https://doi.org/10.1016/j.annemergmed.2019.09.009" @default.
• W2995599975 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31864728" @default.
• W2995599975 hasPublicationYear "2020" @default.
• W2995599975 type Work @default.
• W2995599975 sameAs 2995599975 @default.
• W2995599975 citedByCount "35" @default.
• W2995599975 countsByYear W29955999752020 @default.
• W2995599975 countsByYear W29955999752021 @default.
• W2995599975 countsByYear W29955999752022 @default.
• W2995599975 countsByYear W29955999752023 @default.
• W2995599975 crossrefType "journal-article" @default.
• W2995599975 hasAuthorship W2995599975A5013441728 @default.
• W2995599975 hasAuthorship W2995599975A5014794514 @default.
• W2995599975 hasAuthorship W2995599975A5019783998 @default.
• W2995599975 hasAuthorship W2995599975A5035042761 @default.
• W2995599975 hasAuthorship W2995599975A5039246923 @default.
• W2995599975 hasAuthorship W2995599975A5060219276 @default.
• W2995599975 hasAuthorship W2995599975A5062313023 @default.
• W2995599975 hasAuthorship W2995599975A5081845323 @default.
• W2995599975 hasAuthorship W2995599975A5086516359 @default.
• W2995599975 hasAuthorship W2995599975A5091673971 @default.
• W2995599975 hasBestOaLocation W29955999751 @default.
• W2995599975 hasConcept C126322002 @default.
• W2995599975 hasConcept C141071460 @default.
• W2995599975 hasConcept C141983124 @default.
• W2995599975 hasConcept C142724271 @default.
• W2995599975 hasConcept C159110408 @default.
• W2995599975 hasConcept C168563851 @default.
• W2995599975 hasConcept C1862650 @default.
• W2995599975 hasConcept C204787440 @default.
• W2995599975 hasConcept C27081682 @default.
• W2995599975 hasConcept C2776888751 @default.
• W2995599975 hasConcept C2778074680 @default.
• W2995599975 hasConcept C2780334268 @default.
• W2995599975 hasConcept C2780630273 @default.
• W2995599975 hasConcept C2994186709 @default.
• W2995599975 hasConcept C42219234 @default.
• W2995599975 hasConcept C44249647 @default.
• W2995599975 hasConcept C71924100 @default.
• W2995599975 hasConcept C87813604 @default.
• W2995599975 hasConceptScore W2995599975C126322002 @default.
• W2995599975 hasConceptScore W2995599975C141071460 @default.
• W2995599975 hasConceptScore W2995599975C141983124 @default.
• W2995599975 hasConceptScore W2995599975C142724271 @default.
• W2995599975 hasConceptScore W2995599975C159110408 @default.
• W2995599975 hasConceptScore W2995599975C168563851 @default.
• W2995599975 hasConceptScore W2995599975C1862650 @default.
• W2995599975 hasConceptScore W2995599975C204787440 @default.
• W2995599975 hasConceptScore W2995599975C27081682 @default.
• W2995599975 hasConceptScore W2995599975C2776888751 @default.
• W2995599975 hasConceptScore W2995599975C2778074680 @default.
• W2995599975 hasConceptScore W2995599975C2780334268 @default.
• W2995599975 hasConceptScore W2995599975C2780630273 @default.
• W2995599975 hasConceptScore W2995599975C2994186709 @default.
• W2995599975 hasConceptScore W2995599975C42219234 @default.
• W2995599975 hasConceptScore W2995599975C44249647 @default.
• W2995599975 hasConceptScore W2995599975C71924100 @default.
• W2995599975 hasConceptScore W2995599975C87813604 @default.

• next