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- W2995609156 abstract "Breast cancer is one type of cancer that most often suffered by women. It caused by aberrant cell proliferation that causes an excessive concentration of breast cells. Control of cell proliferation involves multiple pathways, which include components of the cell cycle machinery. It is important to know the behavior changes in cell concentration that can be used as an early indicator of cancer growth. In this paper, we construct a new model of the phase transition regulation on cell cycle to characterize the growth of breast cancer cells in the earlier stage which is indicated by the anomalies of cell proliferation. The model is a 4-dimensional system of the first order ODE that consists of several critical cell cycle phases interaction. We characterize the steady-state of the system analytically and do some numerical simulations to show the cell cycle stability and the excessive growth of breast cells." @default.
- W2995609156 created "2019-12-26" @default.
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- W2995609156 date "2019-01-01" @default.
- W2995609156 modified "2023-10-14" @default.
- W2995609156 title "A mathematical model for phase transition regulation on the cell cycle in early stage of breast cancer" @default.
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- W2995609156 doi "https://doi.org/10.1063/1.5139160" @default.
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