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• W2995674328 abstract "Abstract We evaluated the influence of metabolic syndrome (MS) on acute Trypanosoma cruzi infection. Obese Swiss mice, 70 days of age, were subjected to intraperitoneal infection with 5 × 10 2 trypomastigotes of the Y strain. Cardiovascular, oxidative, inflammatory, and metabolic parameters were evaluated in infected and non-infected mice. We observed higher parasitaemia in the infected obese group (IOG) than in the infected control group (ICG) 13 and 15 days post-infection. All IOG animals died by 19 days post-infection (dpi), whereas 87.5% of the ICG survived to 30 days. Increased plasma nitrite levels in adipose tissue and the aorta were observed in the IOG. Higher INF- γ and MCP-1 concentrations and lower IL-10 concentrations were observed in the IOG compared to those in the ICG. Decreased insulin sensitivity was observed in obese animals, which was accentuated after infection. Higher parasitic loads were found in adipose and hepatic tissue, and increases in oxidative stress in cardiac, hepatic, and adipose tissues were characteristics of the IOG group. Thus, MS exacerbates experimental Chagas disease, resulting in greater damage and decreased survival in infected animals, and might be a warning sign that MS can influence other pathologies." @default.
• W2995674328 created "2019-12-26" @default.
• W2995674328 creator A5016894074 @default.
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• W2995674328 date "2019-12-11" @default.
• W2995674328 modified "2023-10-06" @default.
• W2995674328 title "Metabolic syndrome agravates cardiovascular, oxidative and inflammatory dysfunction during the acute phase of Trypanosoma cruzi infection in mice" @default.
• W2995674328 cites W1512688998 @default.
• W2995674328 cites W1578877546 @default.
• W2995674328 cites W1642046246 @default.
• W2995674328 cites W1842387188 @default.
• W2995674328 cites W1897205387 @default.
• W2995674328 cites W1962019830 @default.
• W2995674328 cites W1968769258 @default.
• W2995674328 cites W1969050381 @default.
• W2995674328 cites W1970389677 @default.
• W2995674328 cites W1973711055 @default.
• W2995674328 cites W1975721026 @default.
• W2995674328 cites W1977645089 @default.
• W2995674328 cites W1980215254 @default.
• W2995674328 cites W1984980185 @default.
• W2995674328 cites W1990653266 @default.
• W2995674328 cites W1992368104 @default.
• W2995674328 cites W1997884694 @default.
• W2995674328 cites W1999410029 @default.
• W2995674328 cites W2002307031 @default.
• W2995674328 cites W2004576893 @default.
• W2995674328 cites W2020421560 @default.
• W2995674328 cites W2025061417 @default.
• W2995674328 cites W2028683797 @default.
• W2995674328 cites W2030484188 @default.
• W2995674328 cites W2031360177 @default.
• W2995674328 cites W2032402870 @default.
• W2995674328 cites W2034626741 @default.
• W2995674328 cites W2036199505 @default.
• W2995674328 cites W2039021392 @default.
• W2995674328 cites W2040933293 @default.
• W2995674328 cites W2046784759 @default.
• W2995674328 cites W2047886690 @default.
• W2995674328 cites W2050459552 @default.
• W2995674328 cites W2055496788 @default.
• W2995674328 cites W2055773624 @default.
• W2995674328 cites W2065389660 @default.
• W2995674328 cites W2066839216 @default.
• W2995674328 cites W2073078616 @default.
• W2995674328 cites W2074697619 @default.
• W2995674328 cites W2075798312 @default.
• W2995674328 cites W2078484489 @default.
• W2995674328 cites W2080215877 @default.
• W2995674328 cites W2080776733 @default.
• W2995674328 cites W2088593927 @default.
• W2995674328 cites W2089770443 @default.
• W2995674328 cites W2090150963 @default.
• W2995674328 cites W2095455974 @default.
• W2995674328 cites W2105985637 @default.
• W2995674328 cites W2116647894 @default.
• W2995674328 cites W2121160088 @default.
• W2995674328 cites W2123289485 @default.
• W2995674328 cites W2123775303 @default.
• W2995674328 cites W2125924084 @default.
• W2995674328 cites W2126100180 @default.
• W2995674328 cites W2137952205 @default.
• W2995674328 cites W2138177096 @default.
• W2995674328 cites W2139722137 @default.
• W2995674328 cites W2140174751 @default.
• W2995674328 cites W2140880230 @default.
• W2995674328 cites W2141632305 @default.
• W2995674328 cites W2147203795 @default.
• W2995674328 cites W2148019592 @default.
• W2995674328 cites W2154268023 @default.
• W2995674328 cites W2158079900 @default.
• W2995674328 cites W2158594043 @default.
• W2995674328 cites W2165942129 @default.
• W2995674328 cites W2223369880 @default.
• W2995674328 cites W2288067680 @default.
• W2995674328 cites W2322248123 @default.
• W2995674328 cites W2409790098 @default.
• W2995674328 cites W2471876202 @default.
• W2995674328 cites W2528762545 @default.
• W2995674328 cites W2560000565 @default.
• W2995674328 cites W2565314403 @default.
• W2995674328 cites W2568434100 @default.
• W2995674328 cites W2572920937 @default.
• W2995674328 cites W2604030747 @default.
• W2995674328 cites W2615666414 @default.
• W2995674328 cites W2760388617 @default.
• W2995674328 cites W2761014800 @default.
• W2995674328 cites W2781978613 @default.
• W2995674328 cites W2789434312 @default.
• W2995674328 cites W2805239032 @default.

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