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- W2995689317 abstract "Biliary hamartoma (BH), with a numerous analogous names, is a congenital bile duct disease that contain cystic dilated bile ducts surrounded by abundant fibrous stroma histologically.1, 2 Ultrasonography (US) is usually the first imaging technique in the detection and characterization of the disease. With the improvement of ultrasound quality, BH is increasing detected and diagnosed correctively without histology. Despite considered a benign lesion, the potential of neoplastic transformation was reported.3 Therefore, it is important to diagnose and monitor the change for patient with BH in clinical practice. Shear wave elastography (SWE) is a noninvasive method with high performance in hepatic cirrhosis diagnosis.4 What is the utility of SWE in the diagnosis and assessment for those patients with BH? In this issue, the article by Yang et al presented the possible utility of SWE in BH diagnosis and evaluation.5 In this study with a series of 14 cases, BH were diagnosed with typical US findings including cloudy echogenicity and comet-tail signs, except one without typical signs. US might be highly accurate in the BH diagnosis with the combined criteria of hyperechoic, sharply delineated parenchymal lesions without acoustic shadows on the periphery of micro- or macrocystic liver lesions, comet-tail artifact and cloudy liver parenchyma.1 For BH diagnosis scenario, SWE might provide the diagnostic confidence of cloudy echogenicity pattern, although seemed not to play an important role in clinical practice. However, SWE might have a role in the assessment of fibrosis stage and cirrhosis diagnosis for BH patients. US is usually the first modality in the diagnosis of cirrhosis with an accuracy of 75% to 87%, which heterogenous parenchyma is one of the important criteria.6 The typical finding of cloudy echogenicity in BH might be mis-interpreted as coarse or heterogenous liver parenchyma pattern which advanced fibrosis and cirrhosis might be over-diagnosed.7 Other US findings in this study included coarse liver parenchyma without splenomegaly in all patients, dull liver angle in two and nodular surface in one patient. There were six patients with chronic viral hepatitis. Although the authors did not provide fibrosis stage of enrolled patients, there might be one or two with the diagnosis of cirrhosis/advanced fibrosis based on US assessment without SWE results. With SWE results, the authors were more confident in the interpretation of cloudy echogenicity for BH diagnosis, instead of extraordinary coarse liver parenchyma pattern in cirrhosis diagnosis. In addition, SWE might provide the important information of fibrosis stage noninvasively for BH patients with chronic viral hepatitis, which will be important in the prognosis evaluation and management.8 To obtain reliable results in fibrosis stage, there is limitation for SWE in BH patients. As mentioned in the discussion, BH might appear as minimal and countless hypoattenuation lesions in round or irregular shape and these lesions might be scattered throughout liver parenchyma.5 When measuring liver stiffness with SWE, the region of interest is recommended to put at a region avoiding bile ducts, large vessels and masses.4 For SWE evaluation in BH patients, it might be hard to find an area to avoid the microcystic lesions scattering liver parenchyma. In addition, an experienced performer adhering to a strict protocol is required to yield reliable results in measuring liver stiffness. In summary, this study reminded clinicians the US diagnostic criteria of BH and the importance in monitoring this benign disease which has the potential of malignant transformation, despite rare with at least 21 cases reported. The authors also suggested the new utility of SWE in differential diagnosis of cloudy echogenicity in BH and heterogenous liver parenchyma pattern in cirrhosis. The most important point however, might be that SWE was useful in the assessment of fibrosis stage which affected the prognosis evaluation and management of chronic viral hepatitis in BH patients." @default.
- W2995689317 created "2019-12-26" @default.
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- W2995689317 date "2019-12-01" @default.
- W2995689317 modified "2023-10-18" @default.
- W2995689317 title "Shear wave elastography for biliary hamartoma: An ancillary to diagnosis?" @default.
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- W2995689317 doi "https://doi.org/10.1002/aid2.13166" @default.
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