Matches in SemOpenAlex for { <https://semopenalex.org/work/W299569729> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W299569729 endingPage "60" @default.
- W299569729 startingPage "655" @default.
- W299569729 abstract "It is well known that adult T-cell leukemia (ATL) is usually refractory to chemotherapy, acute or subacute in clinical course and is accompanied by lethal infections, suggesting a deficiency in cellular immunity. Chemotherapy makes the deficiency in cellular immunity worse, and this is followed by lethal infections. Therefore, a patient with ATL underwent leukapheresis on an IBM 2997 cell separator. A total of 22.3 x 10(11) leukemic T cells was removed. Removal of a large number of leukemic T cells was not associated with improvements in clinical symptoms except for skin eruption, but was not complicated by lethal infections. The peripheral leukocyte count after the 14th procedure began to increase over the prepheresis levels. In the course of frequent leukapheresis, leukemic meningitis occurred. Intrathecal injections of a small dose of antileukemic agents resulted in a rapid reduction of the leukemic T cell count and improvements in clinical symptoms. However, the patient died from cryptococcal sepsis. The survival time was 10 months from clinical onset, 9 months from diagnosis, 9 months from leukapheresis and 5 months from chemotherapy. From this experience, it appears that long-term repeated leukapheresis can decrease lethal infections and extend the survival time." @default.
- W299569729 created "2016-06-24" @default.
- W299569729 creator A5042258996 @default.
- W299569729 creator A5065422794 @default.
- W299569729 creator A5074558395 @default.
- W299569729 creator A5078024344 @default.
- W299569729 creator A5084471714 @default.
- W299569729 date "1982-11-01" @default.
- W299569729 modified "2023-09-27" @default.
- W299569729 title "Trial of long-term leukapheresis in the treatment of adult T-cell leukemia." @default.
- W299569729 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6985175" @default.
- W299569729 hasPublicationYear "1982" @default.
- W299569729 type Work @default.
- W299569729 sameAs 299569729 @default.
- W299569729 citedByCount "0" @default.
- W299569729 crossrefType "journal-article" @default.
- W299569729 hasAuthorship W299569729A5042258996 @default.
- W299569729 hasAuthorship W299569729A5065422794 @default.
- W299569729 hasAuthorship W299569729A5074558395 @default.
- W299569729 hasAuthorship W299569729A5078024344 @default.
- W299569729 hasAuthorship W299569729A5084471714 @default.
- W299569729 hasConcept C10205521 @default.
- W299569729 hasConcept C121332964 @default.
- W299569729 hasConcept C126322002 @default.
- W299569729 hasConcept C141071460 @default.
- W299569729 hasConcept C142424586 @default.
- W299569729 hasConcept C203014093 @default.
- W299569729 hasConcept C2776694085 @default.
- W299569729 hasConcept C2777371436 @default.
- W299569729 hasConcept C2778384902 @default.
- W299569729 hasConcept C2778461978 @default.
- W299569729 hasConcept C28328180 @default.
- W299569729 hasConcept C54355233 @default.
- W299569729 hasConcept C71924100 @default.
- W299569729 hasConcept C86803240 @default.
- W299569729 hasConcept C87355193 @default.
- W299569729 hasConceptScore W299569729C10205521 @default.
- W299569729 hasConceptScore W299569729C121332964 @default.
- W299569729 hasConceptScore W299569729C126322002 @default.
- W299569729 hasConceptScore W299569729C141071460 @default.
- W299569729 hasConceptScore W299569729C142424586 @default.
- W299569729 hasConceptScore W299569729C203014093 @default.
- W299569729 hasConceptScore W299569729C2776694085 @default.
- W299569729 hasConceptScore W299569729C2777371436 @default.
- W299569729 hasConceptScore W299569729C2778384902 @default.
- W299569729 hasConceptScore W299569729C2778461978 @default.
- W299569729 hasConceptScore W299569729C28328180 @default.
- W299569729 hasConceptScore W299569729C54355233 @default.
- W299569729 hasConceptScore W299569729C71924100 @default.
- W299569729 hasConceptScore W299569729C86803240 @default.
- W299569729 hasConceptScore W299569729C87355193 @default.
- W299569729 hasIssue "6" @default.
- W299569729 hasLocation W2995697291 @default.
- W299569729 hasOpenAccess W299569729 @default.
- W299569729 hasPrimaryLocation W2995697291 @default.
- W299569729 hasRelatedWork W2076411732 @default.
- W299569729 hasRelatedWork W2357391729 @default.
- W299569729 hasRelatedWork W2363501795 @default.
- W299569729 hasRelatedWork W2367865661 @default.
- W299569729 hasRelatedWork W2373161014 @default.
- W299569729 hasRelatedWork W2379072718 @default.
- W299569729 hasRelatedWork W2384503702 @default.
- W299569729 hasRelatedWork W2391514770 @default.
- W299569729 hasRelatedWork W2396499999 @default.
- W299569729 hasRelatedWork W2517188707 @default.
- W299569729 hasVolume "7" @default.
- W299569729 isParatext "false" @default.
- W299569729 isRetracted "false" @default.
- W299569729 magId "299569729" @default.
- W299569729 workType "article" @default.