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• W2995762009 abstract "Event Abstract Back to Event Periodontitis and recurrent miscarriage: a case-control study of 41 women with medical history of recurrent miscarriage Angela Morra1*, Simone Palini1, Luca Aquilanti1, Lucrezia Togni1, Luca Montanari1 and Matteo Piemontese1 1 Polytechnical University of Marche, Department of Clinical Specialistic and Dental Sciences, Italy Aim. The aim of this work is to study the relationship between periodontitis and recurrent miscarriage. Materials and Methods. The study was conducted on patients from the Clinic of Obstetrics and Gynecology, Marche Polytechnic University, “G. Salesi” Hospital, Ancona, from 2006 to 2010. Out of 60 women, 41 (mean age 36.0 years) with recurrent miscarriage clinical history were enrolled. The controls were 44 women of the same age range who had not presented a history of recurrent miscarriage. Clinical evaluation parameters for periodontal health status considered were: Probing Depth (PD), Clinical Attack Level (CAL), Bleeding on Probing (BoP), Plaque Index (PI), Gingival Index (GI). Results. The age of the test group ranged from 27 to 44, with a mean age of 36.0. The mean age of the controls group was 35.2. The statistical analysis of the data proved that the age of patients had a normal distribution and there were no significant differences between ages. All participant declared they did not smoke, consume alcohol or drugs before, during and after pregnancy. Furthermore, there were no significant differences between the two groups regarding ethnicity and socio-economic status. There was a statistically significant difference in PI (median: 41% cases, 37% controls), BoP (mean: 55% cases, 19% controls) and GI (mean: 1.27 cases, 0.56 controls). The most important periodontal variable, abortion-related, was BoP. All the other periodontal variables were similar among the groups. Discussion. Miscarriage is the most common complication of pregnancy. The statistical analyzes have shown that the most important factors associated with pregnancy outcomes are BoP and PD, while CAL is related with the presence of periodontitis, but not necessarily in the active phase. Hormonal changes due to increased estrogen and progesterone levels during pregnancy have a special effect on the periodontium. Infection and inflammation appear to be important factors in the pathogenesis of abortion; they are pathogenic processes also involved in periodontitis. The results of recent studies suggest that periodontitis is associated with increased levels of CRP in plasma even in pregnant women. This raises the possibility that CRP can mediate the association between periodontitis and adverse outcomes of pregnancy. Global inflammatory load of periodontitis, associated with hormonal changes in pregnancy, is an additional risk factor in the pathogenesis of recurrent miscarriage. References Loe H, Silness J, Periodontal Disease in Pregnancy: Prevalence and Severity. Acta Odontol Scand 1963 DEC; 21:533-51. Pitiphat W, Joshipura KJ, Rich-Edwards JW, Williams PL, Douglass CW, Gillman MW. Periodontitis and plasma C-reactive protein during pregnancy. J Periodontol. 2006 May;77(5):821-5. Keywords: Periodontitis, periodontal health status, Bleeding on probin, recurrent miscarriage, Pregnacy Conference: 5th National and 1st International Symposium of Italian Society of Oral Pathology and Medicine., Ancona, Italy, 19 Oct - 20 Oct, 2018. Presentation Type: Poster Presentation Topic: Oral Diseases Citation: Morra A, Palini S, Aquilanti L, Togni L, Montanari L and Piemontese M (2019). Periodontitis and recurrent miscarriage: a case-control study of 41 women with medical history of recurrent miscarriage. Front. Physiol. Conference Abstract: 5th National and 1st International Symposium of Italian Society of Oral Pathology and Medicine.. doi: 10.3389/conf.fphys.2019.27.00023 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 24 Oct 2018; Published Online: 09 Dec 2019. * Correspondence: Dr. Angela Morra, Polytechnical University of Marche, Department of Clinical Specialistic and Dental Sciences, Ancona, Italy, fedemurkez@gmail.com Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Angela Morra Simone Palini Luca Aquilanti Lucrezia Togni Luca Montanari Matteo Piemontese Google Angela Morra Simone Palini Luca Aquilanti Lucrezia Togni Luca Montanari Matteo Piemontese Google Scholar Angela Morra Simone Palini Luca Aquilanti Lucrezia Togni Luca Montanari Matteo Piemontese PubMed Angela Morra Simone Palini Luca Aquilanti Lucrezia Togni Luca Montanari Matteo Piemontese Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page." @default.
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• W2995762009 title "Periodontitis and recurrent miscarriage: a case-control study of 41 women with medical history of recurrent miscarriage" @default.
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